Evidence map›Paper›PMID 35429874›Full record

ArticleThe International journal on drug policy2022

Impact of cannabis legalization on healthcare utilization for psychosis and schizophrenia in Colorado.

George Sam Wang, Christine Buttorff, Asa Wilks, Daniel Schwam, Gregory Tung, Rosalie Liccardo Pacula

Open access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

George Sam WangUniversity of Colorado Anschutz Medical Campus Children's, Hospital Colorado Department of Pediatrics 13123 East 16th Ave B251 Aurora CO 80045, United States. Electronic address: george.wang@childrenscolorado.org.
Christine ButtorffRAND Corporation, 1200 S. Hayes St Arlington VA 22202, United States.
Asa WilksRAND Corporation, 1776 Main Street Santa Monica, CA 90407, United States.
Daniel SchwamRAND Corporation, 1200 S. Hayes St Arlington VA 22202, United States.
Gregory TungUniversity of Colorado Anschutz Medical Campus Colorado School of Public Health Department of Health Systems, Management & Policy Program for Injury Prevention, Education and Research (PIPER) Colorado School of Public Health, 13001 E. 17th Place, MS B119, United States.
Rosalie Liccardo PaculaUniversity of Southern California Sol Price School of Public Policy, Schaeffer Center for Health Policy & Economics 635 Downey Way, VPD 514J, Los Angeles, CA 90089-3333, United States.
RAND Corporation · USChildren's Hospital Colorado · USColorado School of Public Health · USUniversity of Southern California · US

Funding

Impact of Marijuana Legalization on Opioid Prescribing and Poisonings in ColoradoR01DA045051 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PACULA, ROSALIE LICCARDO · 2018 to 2020
$1.7M
NIDA NIH HHS R01 DA045051
6 · The paper itself

Abstract

backgroundEmergency department (ED) visits involving psychosis and schizophrenia have increased at a rate exceeding population growth in the United States over the past decade. Research shows a strong dose-response relationship between chronic use of high-potency cannabis and odds of developing symptoms of psychosis. The aim of this study was to evaluate the impact of cannabis legalization on psychosis and schizophrenia-related ED visits in Colorado.

methodsUsing administrative data from Colorado Hospital Association (CHA) on county-level quarterly ED visits between January 1, 2013, and December 31, 2018, we applied a difference-in-difference analysis to examine how new exposure to recreational cannabis dispensaries after 2014 differentially influenced the rate of ED visits for psychosis and schizophrenia, comparing counties with no prior medical cannabis dispensary exposure to counties with low or high medical dispensary exposure.

resultsAs recreational dispensaries per 10,000 residents increased, there was no significant association with the rate of schizophrenia ED visits per capita (incidence rate ratio or IRR: 0.95, 95% CI [0.69, 1.30]) while the rate of psychosis visits increased 24% (IRR: 1.24, 95% CI [1.02, 1.49]). Counties with no previous medical dispensaries experienced larger increases in schizophrenia ED visits than counties already exposed to a low level of medical dispensaries, but this effect was not significant. Counties with low baseline medical exposure had lower increases in rates of psychosis visits than counties with high baseline medical exposure (IRR 0.83, 95% CI [0.69, 0.99]).

conclusionsThere was a positive association between the number of cannabis dispensaries and rates of psychosis ED visits across all counties in Colorado. Although it is unclear whether it is access to products, or the types of products that may be driving this association, our findings suggest there is a potential impact on the mental health of the local population that is observed after cannabis legalization.

Indexed as

CannabisHallucinogensPsychotic DisordersSchizophreniaAnalgesicsColoradoHumansPatient Acceptance of Health CareUnited StatesAnalgesicsHallucinogensCannabisLegalizationMarijuanaMental healthPsychosisSchizophrenia

Identifiers

PMID35429874
PMCPMC9295869
OpenAlexW4224077725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.