Evidence map›Paper›PMID 35429317›Full record

ReviewMolecular biology reports2022

CRISPR-Cas9 based stress tolerance: New hope for abiotic stress tolerance in chickpea (Cicer arietinum).

Muhammad Khuram Razzaq, Muhammad Akhter, Ramala Masood Ahmad, Kaiser Latif Cheema, Aiman Hina, Benjamin Karikari, Ghulam Raza, Guangnan Xing, Junyi Gai, Mohsin Khurshid

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Chickpea (Foods (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. An overview of heat stress in Chickpea (Molecular breeding : new strategies in plant improvement · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Chickpea (Plants (Basel, Switzerland) · 2022
    Review
  13. Review
  14. Improvement of heat stress tolerance in soybean (Frontiers in plant science · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Khuram RazzaqSoybean Research Institute, National Center for Soybean Improvement, Nanjing Agricultural University, 210095, Nanjing, China. khuram.uos@gmail.com.ORCID http://orcid.org/0000-0002-1916-4596
Muhammad AkhterPulses Research Institute, AARI, Faisalabad, Pakistan.
Ramala Masood AhmadDepartment of Plant Breeding and Genetics, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Kaiser Latif CheemaPulses Research Institute, AARI, Faisalabad, Pakistan.
Aiman HinaKohsar University Murree, Admin Block, Kashmir Point 47150, Murree, Pakistan.
Benjamin KarikariDepartment of Crop Science, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, Tamale, Ghana.
Ghulam RazaNational Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan.
Guangnan XingSoybean Research Institute, National Center for Soybean Improvement, Nanjing Agricultural University, 210095, Nanjing, China.
Junyi GaiSoybean Research Institute, National Center for Soybean Improvement, Nanjing Agricultural University, 210095, Nanjing, China.
Mohsin KhurshidDepartment of Microbiology, Government College University, Faisalabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants are subjected to biotic and abiotic stresses regularly, which irreparably harm agricultural production. Eco-friendly and sustainable technology to deal with this challenge is to breed abiotic stress tolerant cultivars. To generate crop plants conferring resistance against stresses, conventional breeding was used in the past, but because of the complex heredity of abiotic stress tolerance traits, such techniques remain insufficient in making greater enhancement. Genome-engineering based on CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR associated protein9) has shown enormous potential in developing climate-resilient cultivars. Likewise, the development of chickpea transgenic lines by knockout of 4CL and REV7 genes exhibits drought tolerance which establishes a foundation for future studies in chickpea. In addition, the CRISPR-Cas9 system can boost yield potential under abiotic stress situations by producing non-transgenic plants having the required characteristics. This review article discusses the validation of gene function based on the CRISPR-Cas9 for the development of abiotic stress-tolerant crop plants, emphasizing the chickpea to open the new ventures of generating abiotic stress-tolerant chickpea varieties.

Indexed as

CicerCRISPR-Cas SystemsPlant BreedingPlantsStress, PhysiologicalAbiotic stress toleranceCRISPR-Cas9Economic yield enhancementNon-transgenic crop plants

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.