Evidence map›Paper›PMID 35429126›Full record

ArticleESC heart failure2022

Renal replacement therapy as a therapeutic option for right heart failure in severe pulmonary arterial hypertension.

Mai Shimbo, Masaru Hatano, Satoshi Ishii, Akihito Saito, Hiroki Yagi, Shun Minatsuki, Hisataka Maki, Eisuke Amiya, Norifumi Takeda, Issei Komuro

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mai ShimboDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Masaru HatanoDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Satoshi IshiiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Akihito SaitoDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Hiroki YagiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Shun MinatsukiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Hisataka MakiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Eisuke AmiyaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Norifumi TakedaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Issei KomuroDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
University of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is a progressively life-threatening disease that causes right heart failure (RHF). Renal dysfunction frequently complicates PAH with RHF and is associated with a worse prognosis. Renal replacement therapy (RRT) may be a therapeutic option, although its efficacy and safety are unclear. We describe a 30-year-old male with severe PAH who developed renal insufficiency and diuretic-refractory volume overload complicated with RHF but was successfully managed with intermittent RRT via a subcutaneously fixed superficial artery for 4 years. RRT led to haemodynamic stability, which enabled us to carefully de-titrate parenteral PAH drugs without worsening RHF. This case highlights that RRT may be a potential alternative for haemodynamic and volume control of refractory fluid retention complicated with RHF in severe PAH cases. Further studies are warranted to gain more insight into patient selection and the optimal timing of RRT in PAH patients with deteriorating RHF.

Indexed as

Heart FailureHypertension, PulmonaryPulmonary Arterial HypertensionAdultArteriesHumansMaleRenal Replacement TherapyAcute kidney injuryPulmonary arterial hypertensionRenal replacement therapyRight heart failureVolume overload

Identifiers

PMID35429126
PMCPMC9288743
OpenAlexW4223980539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.