Evidence map›Paper›PMID 35429095›Full record

ArticleHuman brain mapping2022

Infant brain imaging using magnetoencephalography: Challenges, solutions, and best practices.

Maggie D Clarke, Alexis N Bosseler, Julia C Mizrahi, Erica R Peterson, Eric Larson, Andrew N Meltzoff, Patricia K Kuhl, Samu Taulu

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  6. Expanding the toolkit: OPMs for studying the developing brain.Imaging neuroscience (Cambridge, Mass.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maggie D ClarkeInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-6198-0864
Alexis N BosselerInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.
Julia C MizrahiInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.
Erica R PetersonInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.
Eric LarsonInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-4782-5360
Andrew N MeltzoffInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-8683-0547
Patricia K KuhlInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.
Samu TauluInstitute for Learning & Brain Sciences, University of Washington, Seattle, Washington, USA.
University of Washington · US

Funding

Mechanisms of Brain Dysmorphology in MN1 C-Terminal Truncation Syndrome, a Novel Intellectual Developmental Disability Disorder P50HD103524 · NICHD · UNIVERSITY OF WASHINGTON · PI Sandra E Juul · 2020 to 2026
$9.9M
Scalable Software for Distributed Processing and Visualization of Multi-Site MEG/EEG DatasetsR01NS104585 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MATTI HAMALAINEN · 2018 to 2026
$4.3M
NICHD NIH HHS P50 HD103524NIH HHS R01-NS104585NINDS NIH HHS R01 NS104585
6 · The paper itself

Abstract

The excellent temporal resolution and advanced spatial resolution of magnetoencephalography (MEG) makes it an excellent tool to study the neural dynamics underlying cognitive processes in the developing brain. Nonetheless, a number of challenges exist when using MEG to image infant populations. There is a persistent belief that collecting MEG data with infants presents a number of limitations and challenges that are difficult to overcome. Due to this notion, many researchers either avoid conducting infant MEG research or believe that, in order to collect high-quality data, they must impose limiting restrictions on the infant or the experimental paradigm. In this article, we discuss the various challenges unique to imaging awake infants and young children with MEG, and share general best-practice guidelines and recommendations for data collection, acquisition, preprocessing, and analysis. The current article is focused on methodology that allows investigators to test the sensory, perceptual, and cognitive capacities of awake and moving infants. We believe that such methodology opens the pathway for using MEG to provide mechanistic explanations for the complex behavior observed in awake, sentient, and dynamically interacting infants, thus addressing core topics in developmental cognitive neuroscience.

Indexed as

BrainMagnetoencephalographyBrain MappingChildChild, PreschoolHeadHumansInfantanalysisguidelinesinfantmagnetoencephalographyMEGprocessingrecommendations

Identifiers

PMID35429095
PMCPMC9294291
OpenAlexW4223991601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.