ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2022
Evaluation of inter-user variability in indocyanine green fluorescence angiography to assess gastric conduit perfusion in esophageal cancer surgery.
Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- The use of indocyanine green and near-infrared fluorescence in the detection of metastatic lymph nodes during oesophageal and gastric cancer resection: a systematic review and meta-analysis.Surgical endoscopy · 2025Pooled it
- Quantification of indocyanine green fluorescence angiography in colorectal surgery: a systematic review of the literature.Surgical endoscopy · 2025Pooled it
- Article
- Cross-software comparison shows strong agreement for quantitative indocyanine green fluorescence angiography in reconstructive surgery.Frontiers in surgery · 2026Article
- The Role of Quantitative Indocyanine Green Angiography with Relative Perfusion Ratio in the Assessment of Gastric Conduit Perfusion in Oesophagectomy: A Retrospective Study.Journal of clinical medicine · 2025Article
- Current Practices and Perceptions of Indocyanine Green Fluorescence Guided Liver Surgery: Insights from a Survey of Hepato-Pancreato-Biliary Surgeons in the United Kingdom.Journal of fluorescence · 2025Article
- Intraoperative assessment of anastomotic microcirculation during right hemicolectomy with real-time laser speckle contrast imaging is safe and feasible.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- AUGUR-AIM: Clinical validation of an artificial intelligence indocyanine green fluorescence angiography expert representer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Observational
- Dye-less quantification of tissue perfusion by laser speckle contrast imaging is equivalent to quantified indocyanine green in a porcine model.Surgical endoscopy · 2024Article
- Parathyroid gland identification and angiography classification using simple machine learning methods.BJS open · 2024Article
- Advancing indocyanine green fluorescence flap perfusion assessment via near infrared signal quantification.JPRAS open · 2024Article
- Current status and future trends of real-time imaging in gastric cancer surgery: A literature review.Heliyon · 2024Review
- Surgeon assessment of significant rectal polyps using white light endoscopy alone and in comparison to fluorescence-augmented AI lesion classification.Langenbeck's archives of surgery · 2024Article
- Quantification of indocyanine green near-infrared fluorescence bowel perfusion assessment in colorectal surgery.Surgical endoscopy · 2023Article
- Perfusion assessment by fluorescence time curves in esophagectomy with gastric conduit reconstruction: a prospective clinical study.Surgical endoscopy · 2023Article
- Quantification of Indocyanine Green Fluorescence Imaging in General, Visceral and Transplant Surgery.Journal of clinical medicine · 2023Review
- The role of fluorescence angiography in colonic interposition after esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
- Evaluating clinical near-infrared surgical camera systems with a view to optimizing operator and computational signal analysis.Journal of biomedical optics · 2023Article
- Deconstructing mastery in colorectal fluorescence angiography interpretation.Surgical endoscopy · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indocyanine Green Fluorescence Angiography (ICGFA) has been deployed to tackle malperfusion-related anastomotic complications. This study assesses variations in operator interpretation of pre-anastomotic ICGFA inflow in the gastric conduit. Utilizing an innovative online interactive multimedia platform (Mindstamp), esophageal surgeons completed a baseline opinion-practice questionnaire and proceeded to interpret, and then digitally assign, a distal transection point on 8 ICGFA videos of esophageal resections (6 Ivor Lewis, 2 McKeown). Annotations regarding gastric conduit transection by ICGFA were compared between expert users versus non-expert participants using ImageJ to delineate longitudinal distances with Shapiro Wilk and t-tests to ascertain significance. Expert versus non-expert correlation was assessed via Intraclass Correlation Coefficients (ICC). Thirty participants (13 consultants, 6 ICGFA experts) completed the study in all aspects. Of these, a high majority (29 participants) stated ICGFA should be used routinely with most (21, including 5/6 experts) stating that 11-50 cases were needed for competency in interpretation. Among users, there were wide variations in dosing (0.05-3 mg/kg) and practice impact. Agreement regarding ICGFA video interpretation concerning transection level among experts was 'moderate' (ICC = 0.717) overall but 'good' (ICC = 0.871) among seven videos with Leave One Out (LOO) exclusion of the video with highest disagreement. Agreement among non-experts was moderate (ICC = 0.641) overall and in every subgroup including among consultants (ICC = 0.626). Experts choose levels that preserved more gastric conduit length versus non-experts in all but one video (P = 0.02). Considerable variability exists with ICGFA interpretation and indeed impact. Even adept users may be challenged in specific cases. Standardized training and/or computerized quantitative fluorescence may help better usage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.