ArticleScientific reports2022
Imaging of the medial rectus muscle predicts the development of optic neuropathy in thyroid eye disease.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Prediction models of intravenous glucocorticoids therapy response in thyroid eye disease.European thyroid journal · 2024Pooled it
- Pupillometric alterations in Graves' disease: Beyond thyroid functional status.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Finite Element Analysis of Extraocular Muscle and Adipose-Dominant Pathogenesis in Thyroid Eye Disease With Clinical Implications.Translational vision science & technology · 2026Article
- Volumetric reference data of the orbit: a deep learning MRI analysis in the German national cohort.Scientific reports · 2026Article
- Selective extraocular muscle regression following tocilizumab in active thyroid associated ophthalmopathy: a 3D MRI-based retrospective study.Frontiers in endocrinology · 2026Article
- Quantitative analysis of orbital soft tissue for the detection of dysthyroid optic neuropathy in patients with thyroid-associated ophthalmopathy, based on three-dimensional cube fast spin-echo Flex.Quantitative imaging in medicine and surgery · 2025Article
- A novel nomogram based on orbital MRI parameters for early prediction of dysthyroid optic neuropathy in thyroid-associated ophthalmopathy.BMC ophthalmology · 2025Article
- Predictive demographic and clinical features for the development of dysthyroid optic neuropathy in a multi-ethnic TED population: a retrospective cohort study.Thyroid research · 2025Article
- Correlation between orbital imaging features of thyroid-associated ophthalmopathy and pupillary light reflex measurement.Frontiers in medicine · 2025Article
- Advancements in imaging research in thyroid-associated ophthalmopathy.Frontiers in endocrinology · 2025Review
- Peripheral CD3Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Deep-Learning Based Automated Segmentation and Quantitative Volumetric Analysis of Orbital Muscle and Fat for Diagnosis of Thyroid Eye Disease.Investigative ophthalmology & visual science · 2024Article
- Effects of various extraocular muscle enlargement patterns on muscle diameter index in graves ophthalmopathy patients: a retrospective cohort study.Scientific reports · 2023Article
- Reduced contrast sensitivity function correlated with superficial retinal capillary plexus impairment in early stage of dysthyroid optic neuropathy.Eye and vision (London, England) · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Goal of the study was to evaluate bony orbit remodeling and extraocular muscle (EOM) volume in thyroid eye disease (TED) and their role as predicting factors for development of dysthyroid optic neuropathy (DON). Orbital computed tomography of 92 patients with TED with (76 orbits) or without DON (98 orbits) were retrospectively evaluated. Orbits (n = 40) of subjects without TED served as controls. Measurements of the bony orbit as well as EOM volume were incorporated into a generalized linear mixed model to predict DON. The angle of the medial orbital wall was significantly smaller (p < 0.001) in patients with TED (- 2.3 ± 3.6°) compared to patients with TED + DON (1.0 ± 4.1°). Both groups differed significantly from controls (- 4.2 ± 2.7°). Bowing of the medial orbital wall correlated positively with muscle volume (r = 0.564; p < 0.001). Total EOM volume was significantly larger in TED + DON (7.6 ± 2.5cm
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