Evidence map›Paper›PMID 35428694›Full record

ArticleBMJ evidence-based medicine2023

Good or best practice statements: proposal for the operationalisation and implementation of GRADE guidance.

Omar Dewidar, Tamara Lotfi, Miranda W Langendam, Elena Parmelli, Zuleika Saz Parkinson, Karla Solo, Derek K Chu, Joseph L Mathew, Elie A Akl, Romina Brignardello-Petersen and 29 more

Abstract read
In one paragraph

Article in BMJ evidence-based medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 20 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 20 syntheses or guidelines pooled it.

  1. Reducing distress during vaccine injections: 2026 clinical practice guideline update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Guideline
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  12. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
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  14. Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV - CDC Recommendations, United States, 2025.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2025
    Guideline
  15. Pooled it
  16. Managing obesity in children: a clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  17. Pooled it
  18. Guideline
  19. Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Guideline
  20. Pooled it

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors.

Omar DewidarMethods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada.ORCID 0000-0001-6420-887X
Tamara LotfiDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Miranda W LangendamAmsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
Elena ParmelliJoint Research Centre, European Commission, Ispra, Lombardia, Italy.
Zuleika Saz ParkinsonInstituto de Salud Carlos III, Agencia de Evaluación de Tecnologías Sanitarias, Madrid, Spain.
Karla SoloDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Derek K ChuDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-8269-4496
Joseph L MathewDepartment of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India.
Elie A AklDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Romina Brignardello-PetersenDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Reem A MustafaInternal Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, Kansas, USA.
Lorenzo MojaDepartment of Health Product Policy and Standards, World Health Organization, Geneva, Switzerland.
Alfonso IorioDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Yuan ChiYealth Network, Beijing Yealth Technology Co., Ltd, Beijing, China.
Carlos Canelo-AybarIberoamerican Cochrane Center, Biomedical Research Institute Sant Pau-CIBERESP, Barcelona, Spain.
Tamara KredoCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.ORCID 0000-0001-7115-9535
Justine KarpusheffNational Institute for Health and Care Excellence, London, UK.
Alexis F TurgeonCentre de Recherche du Centre Hospitalier Affilié Universitaire de Québec (CHA), CHA-Hôpital de l'Enfant-Jésus, Université Laval, Québec City, Québec, Canada.
Pablo Alonso-CoelloIberoamerican Cochrane Center, Biomedical Research Institute Sant Pau-CIBERESP, Barcelona, Spain.
Wojtek WierciochDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Annette GerritsenCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.
Miloslav KlugarCzech National Centre for Evidence-Based Healthcare and Knowledge Translation, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.ORCID 0000-0002-2804-7295
María Ximena RojasDepartment of Clinical Epidemiology and Public Health, Institut d'Investigació Biomèdica Sant Pau IIB Sant Pau, Barcelona, Spain.
Peter TugwellDepartment of Medicine, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Vivian Andrea WelchMethods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada.ORCID 0000-0002-5238-7097
Kevin PottieDeparatment of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Zachary MunnJoanna Briggs Institute, University of Adelaide, Adelaide, South Australia, Australia.
Robby NieuwlaatDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Nathan FordDepartment of HIV, Hepatitis and Sexually Transmitted Infections, World Health Organization, Geneva, Switzerland.
Adrienne StevensDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Joanne KhabsaClinical Research Institute, American University of Beirut, Beirut, Lebanon.ORCID 0000-0002-4336-3501
Zil NasirDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Grigorios LeontiadisMichael G DeGroote Cochrane Canada and McMaster GRADE Centres, McMaster University, Hamilton, Ontario, Canada.
Joerg MeerpohlCochrane Germany, Cochrane Germany Foundation, Freiburg, Germany.
Thomas PiggottDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Amir QaseemAmerican College of Physicians, Philadelphia, Pennsylvania, USA.
Micayla MatthewsDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Holger J SchünemannDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada schuneh@mcmaster.ca.ORCID 0000-0003-3211-8479
eCOVID-19 recommendations map collaborators

Funding

World Health Organization 001
6 · The paper itself

Abstract

An evidence-based approach is considered the gold standard for health decision-making. Sometimes, a guideline panel might judge the certainty that the desirable effects of an intervention clearly outweigh its undesirable effects as high, but the body of supportive evidence is indirect. In such cases, the application of the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach for grading the strength of recommendations is inappropriate. Instead, the GRADE Working Group has recommended developing ungraded best or good practice statement (GPS) and developed guidance under which circumsances they would be appropriate.Through an evaluation of COVID-1- related recommendations on the eCOVID Recommendation Map (COVID-19.recmap.org), we found that recommendations qualifying a GPS were widespread. However, guideline developers failed to label them as GPS or transparently report justifications for their development. We identified ways to improve and facilitate the operationalisation and implementation of the GRADE guidance for GPS.Herein, we propose a structured process for the development of GPSs that includes applying a sequential order for the GRADE guidance for developing GPS. This operationalisation considers relevant evidence-to-decision criteria when assessing the net consequences of implementing the statement, and reporting information supporting judgments for each criterion. We also propose a standardised table to facilitate the identification of GPS and reporting of their development. This operationalised guidance, if endorsed by guideline developers, may palliate some of the shortcomings identified. Our proposal may also inform future updates of the GRADE guidance for GPS.

Indexed as

COVID-19Evidence-Based MedicineHumansResearch DesignCOVID-19Evidence-Based Practice

Identifiers

PMID35428694
PMCPMC10313969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.