Evidence map›Paper›PMID 35428274›Full record

ArticleTrials2022

Comparison of the open kinetic chain and closed kinetic chain strengthening exercises on pain perception and lower limb biomechanics of patients with mild knee osteoarthritis: a randomized controlled trial protocol.

Wei Hui Ng, Nazatul Izzati Jamaludin, Farhah Nadhirah Aiman Sahabuddin, Shaifuzain Ab Rahman, Amran Ahmed Shokri, Shazlin Shaharudin

3 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04678609 naunknown statusnot on this map

Effects of Open and Closed Kinetic Chain Exercise on Functional Outcomes and Lower Limb Biomechanics in Mild Knee Osteoarthritis Patients

TypeinterventionalSponsorUniversiti Sains MalaysiaRan2020 to 2022Enrolled66ConditionsOsteoarthritis, Knee, Aging ProblemsArmsExercise
NCT05877703 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Open Versus Close Kinetic Chain Exercise Training Program With Lifestyle Modification and Patient's Education in Grade 3 Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled24ConditionsKnee OsteoarthritisArmsclose kinetic chain exercises, open kinetic chain exercises
NCT06511557 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparative Effect of Non Immersive Virtual Reality Based Training (Xbox Kinect) and Kinetic Chain Exercises in Patient With Knee Osteoarthritis.

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled46ConditionsKnee OsteoarthritisArmsNon immersive virtual reality ( xbox kinetic), Kinetic chain exercises
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Effects of Sanqi Shengyu External Application Cream and Pulsed Electromagnetic Field on Knee Osteoarthritis in Older Adults: A Randomized Controlled Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wei Hui NgSchool of Health Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.
Nazatul Izzati JamaludinSchool of Health Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.
Farhah Nadhirah Aiman SahabuddinSchool of Health Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.
Shaifuzain Ab RahmanSchool of Medical Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.
Amran Ahmed ShokriSchool of Medical Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.
Shazlin ShaharudinSchool of Health Sciences, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia. shazlin@usm.my.ORCID http://orcid.org/0000-0001-5583-7631
Hospital Universiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical recommendations suggest exercises as the main treatment modality for patients with knee osteoarthritis (OA). This study aimed to compare the effects of two different exercise interventions, i.e., open kinetic chain (OKC) and closed kinetic chain (CKC) exercises, on the pain and lower limb biomechanics of patients with mild knee OA.

methodA total of 66 individuals with painful early knee OA, aged 50 years and above, with body mass index (BMI) between 18.9kg/m DISCUSSION: The present study will compare the effects of two different home-based exercise intervention programs among patients with mild knee OA. The study findings will provide vital information that can be used to design an effective exercise program that aims at delaying the OA progression.

trial registrationThe protocol was registered on 22 December 2020 at ClinicalTrials.gov (registration number: NCT04678609 ).

Indexed as

Osteoarthritis, KneeBiomechanical PhenomenaExercise TherapyHumansLower ExtremityPainPain PerceptionQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeHome-based exercise programKnee osteoarthritisPhysiotherapy

Identifiers

PMID35428274
PMCPMC9012068
OpenAlexW4223959445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.