Evidence map›Paper›PMID 35428265›Full record

ArticleRadiation oncology (London, England)2022

Retrospective evaluation of a robust hybrid planning technique established for irradiation of breast cancer patients with included mammary internal lymph nodes.

Marina Hennet, Stephan Radonic, Uwe Schneider, Matthias Hartmann

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marina HennetDepartment of Radiotherapy, Klinik Hirslanden AG, Rain 34, 5000, Aarau, Switzerland. Marina.Hennet@hirslanden.ch.ORCID http://orcid.org/0000-0001-7175-4879
Stephan RadonicDepartment of Physics, University of Zürich, Zürich, Switzerland.
Uwe SchneiderDepartment of Radiotherapy, Klinik Hirslanden AG, Rain 34, 5000, Aarau, Switzerland.
Matthias HartmannDepartment of Radiotherapy, Klinik Hirslanden AG, Rain 34, 5000, Aarau, Switzerland.
University of Zurich · CHKlinik Hirslanden · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe irradiation of breast cancer patients with included internal mammary lymph nodes challenges radiation planning with regard to robustness and protection of OARs. In this publication, a feasible hybrid radiation technique is presented with a retrospective dosimetric and radiobiological analysis of patient data of our institute from 2016 to 2020 and robustness analysis.

methodsThe proposed hybrid irradiation technique consists of two IMRT tangents and two partial VMAT fields. The retrospective dosimetric and radiobiological evaluation are made for 217 patient treatments (right- and left-sided). The robustness is evaluated regarding an artificial swelling from 0.4 to 1.5 cm for a random example patient and compared to a pure VMAT planning technique with use of a virtual bolus. The out of field stray dose is calculated for a selected patient plan and compared to alternative radiation techniques.

resultsThe coverage D

conclusionsThe feasibility of the proposed planning technique is shown by treating many patients with this technique at our radiotherapy department. The hybrid radiation technique shows a good sparing of the OARs in the retrospective analysis and is robust with regards to a breast swelling of up to 1.5 cm. The slightly higher stray dose of the hybrid technique compared to a pure VMAT technique originates from higher number of MUs and lower conformity.

Indexed as

Breast NeoplasmsRadiotherapy, Intensity-ModulatedFemaleHumansLymph NodesOrgans at RiskPlanning TechniquesRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesBreast cancerHybridIMRTMammary internaOptimizationRadiotherapyTreatment planningVMAT

Identifiers

PMID35428265
PMCPMC9013158
OpenAlexW4223911043

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.