Evidence map›Paper›PMID 35427920›Full record

ReviewCurrent opinion in chemical biology2022

Iron-responsive riboswitches.

Jiansong Xu, Joseph A Cotruvo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Microbial metal physiology: ions to ecosystems.Nature reviews. Microbiology · 2025
    Review
  2. Review
  3. Prokaryotic homeostasis - a solution to thrive and survive.Frontiers in molecular biosciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jiansong XuDepartment of Chemistry and Center for RNA Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.
Joseph A CotruvoDepartment of Chemistry and Center for RNA Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: juc96@psu.edu.

Funding

New tools to probe iron and manganese homeostasis in bacterial and eukaryotic cellsR35GM138308 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI COTRUVO, JOSEPH ALFRED · 2020 to 2024
$1.9M
NIGMS NIH HHS R35 GM138308
6 · The paper itself

Abstract

All cells must manage deficiency, sufficiency, and excess of essential metal ions. Although iron has been one of most important metals in biology for billions of years, the mechanisms by which bacteria cope with high intracellular iron concentrations are only recently coming into focus. Recent work has suggested that an RNA riboswitch (czcD or "NiCo"), originally thought to respond specifically to Co

Indexed as

RiboswitchFerrous CompoundsHumansIonsIronMetalsFerrous CompoundsIonsIronMetalsRiboswitchIron overloadIrving–Williams seriesMetal homeostasisMetalloregulationRNA

Identifiers

PMID35427920
PMCPMC9133107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.