Evidence map›Paper›PMID 35427192›Full record

ArticleAutophagy2023

Atg1-mediated Atg11 phosphorylation is required for selective autophagy by regulating its association with receptor proteins.

Weijing Yao, Yixing Li, Yingcong Chen, Yuting Chen, Yu Xie, Miaojuan Ye, Ying Zhang, Xiangjun Chen, Xiaoyong Wu, Yuyao Feng and 4 more

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Core principles of autophagy initiation mechanisms.Nature structural & molecular biology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Omic AI reveals new autophagy regulators from the Atg1 interactome inFrontiers in cell and developmental biology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Mec1 regulates PAS recruitment of Atg13 via direct binding with Atg13 during glucose starvation-induced autophagy.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Review
  14. Autophagy as a dual-faced host response to viral infections.Frontiers in cellular and infection microbiology · 2023
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Weijing YaoDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yixing LiDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yingcong ChenDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yuting ChenDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yu XieCollege of Chemistry and Bio-Engineering, Yichun University, Yichun, China.
Miaojuan YeXinyuan Institute of Medicine and Biotechnology, School of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Ying ZhangEye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, Jiefang Road, Hangzhou, China.
Xiangjun ChenEye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, Jiefang Road, Hangzhou, China.
Xiaoyong WuDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yuyao FengDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhi HongZJU-UoE Institute, Zhejiang University School of Medicine, Zhejiang University, Haining, China.
Yigang WangXinyuan Institute of Medicine and Biotechnology, School of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Wei LiuDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-8033-4718
Cong YiDepartment of Biochemistry and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0001-6853-6563
First Affiliated Hospital Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNZhejiang Sci-Tech University · CNYichun University · CNZhejiang University-University of Edinburgh Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atg11 is an adaptor protein required for the induction of selective autophagy via receptor binding. However, our understanding of the molecular mechanisms by which it regulates selective autophagy remains incomplete. Here, we show that Atg11 is phosphorylated by Atg1. Rapamycin treatment or starvation conditions induced slower electrophoretic mobility of Atg11 in an Atg1 kinase activity-dependent manner. Through

Indexed as

AutophagyMacroautophagyAMP-Activated Protein KinasesAutophagy-Related Protein-1 HomologAutophagy-Related ProteinsCarrier ProteinsPhosphorylationAMP-Activated Protein KinasesAutophagy-Related Protein-1 HomologAutophagy-Related ProteinsCarrier ProteinsAtg1Atg11phosphorylationreceptorselective autophagy

Identifiers

PMID35427192
PMCPMC9809958
OpenAlexW4224077051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.