Evidence map›Paper›PMID 35427158›Full record

ArticleScience advances2022

One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk.

Christine Klein, Max Borsche, Alexander Balck, Bandik Föh, Johann Rahmöller, Elke Peters, Jan Knickmann, Miranda Lane, Eva-Juliane Vollstedt, Susanne A Elsner and 20 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Observational
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Serum Metabolomic Profiling of Patients with Lipedema.International journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 5 institutions in 2 countries.

Christine KleinInstitute of Neurogenetics, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0003-2102-3431
Max BorscheInstitute of Neurogenetics, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0002-9651-5986
Alexander BalckInstitute of Neurogenetics, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0003-3967-0282
Bandik FöhInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-8793-7418
Johann RahmöllerInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-5683-4181
Elke PetersInstitute of Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.
Jan KnickmannInstitute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-9836-4587
Miranda LaneInstitute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany.
Eva-Juliane VollstedtInstitute of Neurogenetics, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0002-6898-9201
Susanne A ElsnerInstitute of Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.
Nadja KädingDepartment of Infectious Diseases and Microbiology, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Susanne HauswaldtDepartment of Infectious Diseases and Microbiology, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Tanja LangeDepartment of Rheumatology and Clinical Immunology, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0001-8309-2112
Jennifer E HundtLübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany.
Selina LehrianInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.
Julia GieseInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-6039-8565
Alexander MischnikHealth Protection Authority, Lübeck, Germany.ORCID 0000-0003-2326-4132
Stefan NiemannResearch Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID 0000-0002-6604-0684
Florian MaurerResearch Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID 0000-0001-8353-5964
Susanne HomolkaResearch Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID 0000-0003-4972-5638
Laura PaulowskiResearch Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID 0000-0002-6662-4196
Jan KramerInstitute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany.
Christoph TwestenPerfood GmbH, Lübeck, Germany.
Christian SinaInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-7640-1220
Gabriele Gillessen-KaesbachUniversity of Lübeck, Lübeck, Germany.
Hauke BuschLübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany.ORCID 0000-0003-4763-4521
Marc EhlersInstitute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-5383-8603
Stefan TaubeInstitute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-9159-3651
Jan RuppDepartment of Infectious Diseases and Microbiology, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.ORCID 0000-0001-8722-1233
Alexander KatalinicInstitute of Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.ORCID 0000-0003-0490-1554
University of Lübeck · DEUniversity Hospital Schleswig-Holstein · DEResearch Center Borstel - Leibniz Lung Center · DEGerman Center for Infection Research · DEUniversity of Camagüey · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With newly rising coronavirus disease 2019 (COVID-19) cases, important data gaps remain on (i) long-term dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates in fixed cohorts (ii) identification of risk factors, and (iii) establishment of effective surveillance strategies. By polymerase chain reaction and antibody testing of 1% of the local population and >90,000 app-based datasets, the present study surveilled a catchment area of 300,000 inhabitants from March 2020 to February 2021. Cohort (56% female; mean age, 45.6 years) retention was 75 to 98%. Increased risk for seropositivity was detected in several high-exposure groups, especially nurses. Unreported infections dropped from 92 to 29% during the study. "Contact to COVID-19-affected" was the strongest risk factor, whereas public transportation, having children in school, or tourism did not affect infection rates. With the first SARS-CoV-2 cohort study, we provide a transferable model for effective surveillance, enabling monitoring of reinfection rates and increased preparedness for future pandemics.

Identifiers

PMID35427158
PMCPMC9012459
OpenAlexW4223979415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.