Evidence map›Paper›PMID 35427152›Full record

ArticleScience advances2022

Combinatorial wound healing therapy using adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation.

So Yun Lee, Sangheon Jeon, Young Woo Kwon, Mina Kwon, Moon Sung Kang, Keum-Yong Seong, Tae-Eon Park, Seung Yun Yang, Dong-Wook Han, Suck Won Hong and 1 more

Abstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A multi therapy bioelectronic wound dressing.npj biomedical innovations · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

So Yun LeeSchool of Chemical Engineering, College of Engineering, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-1810-919X
Sangheon JeonDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-4181-8306
Young Woo KwonDepartment of Nano-fusion Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0003-0583-3629
Mina KwonSchool of Chemical Engineering, College of Engineering, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0003-2283-413X
Moon Sung KangDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-6375-5038
Keum-Yong SeongDepartment of Biomaterials Science, College of Natural Resources and Life Science, Pusan National University, Miryang 50463, Republic of Korea.
Tae-Eon ParkSchool of Chemical Engineering, College of Engineering, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-1189-0921
Seung Yun YangDepartment of Biomaterials Science, College of Natural Resources and Life Science, Pusan National University, Miryang 50463, Republic of Korea.
Dong-Wook HanDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-8314-1981
Suck Won HongDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-7291-1020
Ki Su KimSchool of Chemical Engineering, College of Engineering, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-6289-9467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is the dynamic tissue regeneration process replacing devitalized and missing tissue layers. With the development of photomedicine techniques in wound healing, safe and noninvasive photobiomodulation therapy is receiving attention. Effective wound management in photobiomodulation is challenged, however, by limited control of the geometrical mismatches on the injured skin surface. Here, adhesive hyaluronic acid-based gelatin nanofibrous membranes integrated with multiple light-emitting diode (LED) arrays are developed as a skin-attachable patch. The nanofibrous wound dressing is expected to mimic the three-dimensional structure of the extracellular matrix, and its adhesiveness allows tight coupling between the wound sites and the flexible LED patch. Experimental results demonstrate that our medical device accelerates the initial wound healing process by the synergetic effects of the wound dressing and LED irradiation. Our proposed technology promises progress for wound healing management and other biomedical applications.

Identifiers

PMID35427152
PMCPMC9012471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.