Evidence map›Paper›PMID 35426599›Full record

ArticleAnnals of nuclear medicine2022

Burçak Yılmaz, Selçuk Şahin, Nurhan Ergül, Yunus Çolakoğlu, Halil Fırat Baytekin, Doğukan Sökmen, Volkan Tuğcu, Ali İhsan Taşçı, Tevfik Fikret Çermik

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of nuclear medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
  5. Single Photon Emission Computed Tomography Tracer.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Burçak YılmazHealth Sciences University, Basaksehir Cam and Sakura City Hospital, Clinic of Nuclear Medicine, Başakşehir Mahallesi G-434 Caddesi No: 2L, Başakşehir, Istanbul, Turkey. drburcak@gmail.com.ORCID http://orcid.org/0000-0002-6979-0990
Selçuk ŞahinHealth Sciences University, Bakırkoy Dr. Sadi Konuk Research and Training Hospital, Clinic of Urology, Istanbul, Turkey.
Nurhan ErgülHealth Sciences University, Istanbul Research and Training Hospital, Clinic of Nuclear Medicine, Istanbul, Turkey.
Yunus ÇolakoğluHealth Sciences University, Basaksehir Cam and Sakura City Hospital, Clinic of Urology, Istanbul, Turkey.
Halil Fırat BaytekinHealth Sciences University, Bakırkoy Dr. Sadi Konuk Research and Training Hospital, Clinic of Pathology, Istanbul, Turkey.
Doğukan SökmenUrology Department, Memorial Hospital, Istanbul, Turkey.
Volkan TuğcuUrology Department, Memorial Hospital, Istanbul, Turkey.
Ali İhsan TaşçıHealth Sciences University, Bakırkoy Dr. Sadi Konuk Research and Training Hospital, Clinic of Urology, Istanbul, Turkey.
Tevfik Fikret ÇermikHealth Sciences University, Istanbul Research and Training Hospital, Clinic of Nuclear Medicine, Istanbul, Turkey.
Sağlık Bilimleri Üniversitesi · TRBakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRIstanbul Memorial Hospital · TR

Funding

Health Sciences University, Istanbul, Turkey Scientific Research Project (2018 / 076)
6 · The paper itself

Abstract

objectiveThe feasibility of tracer production of

methodsFifteen primary PCa patients with intermediate- or high-risk score according to D'Amico risk stratification who had PSMA receptor affinity with Ga-68 PSMA-11 PET/CT were enrolled. After

resultsPhysiological radiotracer distribution was similar for both imaging modalities. PCa lesions were much more visible on PET/CT. Metastatic LNs could not be visualized with SPECT/CT. Eighteen of 297 totally dissected LNs were metastatic, which were exactly the same with per-operative probe counts with sensitivity, specificity, accuracy, and negative and positive predictive value of all 100%. The median follow-up was 23.5 ± 4.6 months. tPSA reduction was > 98%. The 2.5 years biochemical recurrence-free survival, PCa-specific treatment-free survival and overall survival rates were 86,7%, 66,7% and 100%, respectively.

conclusionTc-99 m-PSMA-RG-RALRP is a promising technique for extended pelvic lymph node dissection (ePLND) during robotic surgery, which may shorten the operation time and reduce complication risks. If LN metastases is detected during surgery with PSMA-targeted probe, it may be an early indicator of PCa-spesific treatment planning. Tc-99 m-PSMA-I&S SPECT/CT is not as successful as Ga-68 PSMA-11 PET/CT for diagnosis of primary PCA lesions or LN metastases.

Indexed as

Prostatic NeoplasmsRoboticsRobotic Surgical ProceduresGallium IsotopesGallium RadioisotopesHumansLymphatic MetastasisLymph Node ExcisionMalePositron Emission Tomography Computed TomographyProstateProstatectomyTechnetiumGallium-68gallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesTechnetiumGamma probePET/CTProstate-specific membrane antigenRadioguided surgeryRobot-assisted laparoscopic radical prostatectomySPECT/CT

Identifiers

PMID35426599
OpenAlexW4224048452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.