Evidence map›Paper›PMID 35426589›Full record

SynthesisInternational urology and nephrology2022

Safety and efficacy of hemodialysis and peritoneal dialysis in treating end-stage diabetic nephropathy: a meta-analysis of randomized controlled trials.

Menglin Zou, Jianjun Xie, Lili Lan, Yiye Zhang, Liqing Tian, Man Chen, Yan Yan

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Hyperkalemia in Severe Burn Injuries: Pathogenesis and Therapeutic Advances.Journal of community hospital internal medicine perspectives · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Menglin ZouDepartment of Nephrology, Gaoxin Branch of the First Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, China.
Jianjun XieHospital of Jiangxi Provincial Armed Police Corps, Nanchang, People's Republic of China.
Lili LanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Avenue, Nanchang City, Jiangxi Province, China.
Yiye ZhangDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Avenue, Nanchang City, Jiangxi Province, China.
Liqing TianDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Avenue, Nanchang City, Jiangxi Province, China.
Man ChenDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Avenue, Nanchang City, Jiangxi Province, China.
Yan YanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Avenue, Nanchang City, Jiangxi Province, China. kiddoc@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPresent investigation aims to elucidate safety and efficacy of hemodialysis as well as peritoneal dialysis in treating end-stage diabetic nephropathy.

methodsWe searched various databases for articles from the database starting date to October 2019. The analysis involved studies that contained outcomes of hemodialysis and peritoneal dialysis in the treatment of end-stage diabetic nephropathy. A total of 12 randomized controlled trials (RCTs) with 932 participants were collected.

resultsMeta-analysis results suggested that comparing with peritoneal dialysis group, hemodialysis group had a higher incidence of cardiovascular and cerebrovascular events and bleeding complications. There was no statistically significant difference regarding the infection (P = 0.71) or malnutrition (P = 0.53) incidence between the two forms of dialysis. Hemodialysis could better improve the levels of albumin [mean difference (MD) = 6.80, 95% CI = (4.17-9.44)] and hemoglobin [MD = 3.40, 95% CI = (0.94-5.86)] than peritoneal dialysis after 3 months or more.

conclusionsIn treating end-stage diabetic nephropathy patients, peritoneal dialysis had a lower incidence of cardiovascular and cerebrovascular events, as well as bleeding complication than hemodialysis. However, hemodialysis could better improve albumin and hemoglobin levels than peritoneal dialysis after 3 months.

Indexed as

Diabetes MellitusDiabetic NephropathiesKidney Failure, ChronicPeritoneal DialysisAlbuminsHemoglobinsHumansRandomized Controlled Trials as TopicRenal DialysisAlbuminsHemoglobinsEnd-stage diabetic nephropathyHemodialysisPeritoneal dialysisRandomized controlled trials

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.