Evidence map›Paper›PMID 35426507›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Psychopathological symptoms as precursors of depressive symptoms in adolescence: a prospective analysis of the GINIplus and LISA birth cohort studies.

Ellen Greimel, Lena Adams, Carolin Zsigo, Dietrich Berdel, Andrea von Berg, Sibylle Koletzko, Carl-Peter Bauer, Tamara Schikowski, Gunda Herberth, Joachim Heinrich and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Ellen GreimelDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich, Waltherstr. 23, 80337, Munich, Germany. Ellen.Greimel@med.uni-muenchen.de.ORCID http://orcid.org/0000-0002-9916-9230
Lena AdamsDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich, Waltherstr. 23, 80337, Munich, Germany.
Carolin ZsigoDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich, Waltherstr. 23, 80337, Munich, Germany.
Dietrich BerdelDepartment of Pediatrics, Research Institute, Marien-Hospital Wesel, Wesel, Germany.
Andrea von BergDepartment of Pediatrics, Research Institute, Marien-Hospital Wesel, Wesel, Germany.
Sibylle KoletzkoDepartment of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.
Carl-Peter BauerDepartment of Pediatrics, Technical University of Munich, Munich, Germany.
Tamara SchikowskiIUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
Gunda HerberthDepartment of Environmental Immunology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Joachim HeinrichInstitute of Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, 85764, Neuherberg, Germany.
Gerd Schulte-KörneDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich, Waltherstr. 23, 80337, Munich, Germany.
Marie StandlInstitute of Epidemiology, Helmholtz Zentrum München-German Research Centre for Environmental Health, 85764, Neuherberg, Germany.
Ludwig-Maximilians-Universität München · DEMarien Hospital Wesel · DEHelmholtz Centre for Environmental Research · DEHelmholtz Zentrum München · DELeibniz Institute of Environmental Medicine · DELMU Klinikum · DETechnical University of Munich · DEThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDepressive symptoms are highly prevalent in adolescence, highlighting the need for early identification of precursors. Research into psychopathological symptoms predicting depressive psychopathology in adolescents is therefore of great relevance. Moreover, given that the prevalence of depressive symptomatology in adolescence shows marked differences between girls and boys, insight into potential sex-specific differences in precursors is important.

methodsThis study examined the relationships between emotional problems, conduct problems, hyperactivity/inattention, peer problems, and difficulties in prosocial behaviour at age 10 (Strengths and Difficulties Questionnaire), and the presence of depressive symptoms at age 15 (Depression Screener for Teenagers). Using data from 2824 participants of the GINIplus and LISA birth cohorts, the association of each SDQ subscale at age 10 years with the presence of depressive symptoms at age 15 years was analyzed using sex-specific logistic regression, adjusting for potential confounders.

resultsEmotional problems [odds ratio (OR) 1.99, p = 0.002 for boys and OR 1.77, p < 0.001 for girls] and peer problems (OR 2.62, p < 0.001 for boys, OR 1.91, p = 0.001 for girls) at age 10 showed an increased risk for the presence of depressive symptoms at age 15. Additionally, boys with conduct problems at age 10 were at greater risk of showing depressive symptoms in adolescence (OR 2.50, p < 0.001). DISCUSSION: Based on the identified prospective relationships in our study, it might be of particular importance to tailor prevention approaches during childhood to peer and emotional problems to reduce the risk of depressive psychopathology in adolescence. Moreover, particularly in boys, it seems important to also target conduct problems in childhood as a precursor of depressive symptoms in the adolescent period.

Indexed as

DepressionMental DisordersAdolescentBirth CohortChildFemaleHumansMalePsychopathologySurveys and QuestionnairesAdolescenceDepressive symptomsEpidemiologyProspective analysisStrengths and Difficulties Questionnaire

Identifiers

PMID35426507
PMCPMC9288954
OpenAlexW4223970530

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.