Evidence map›Paper›PMID 35426488›Full record

ArticleInternational forum of allergy & rhinology2022

Particulate matter air pollution exposure disrupts the Nrf2 pathway in sinonasal epithelium via epigenetic alterations in a murine model.

Bongsoo Park, Nyall R London, Anuj Tharakan, Palanivel Rengasamy, Sanjay Rajagopalan, Shyam Biswal, Jayant M Pinto, Murugappan Ramanathan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025
    Review
  5. Chitosan Nanoparticle-EncapsulatedInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. The Effects of Wildfire Smoke on Asthma and Allergy.Current allergy and asthma reports · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Bongsoo ParkDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore MD, USA.
Nyall R LondonDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine Baltimore, Maryland, USA.
Anuj TharakanDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine Baltimore, Maryland, USA.
Palanivel RengasamyCardiovascular Research Institute, Case Western Reserve University, Cleveland, Ohio, USA.
Sanjay RajagopalanCardiovascular Research Institute, Case Western Reserve University, Cleveland, Ohio, USA.
Shyam BiswalDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore MD, USA.
Jayant M PintoDivision of Otolaryngology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA.
Murugappan RamanathanDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine Baltimore, Maryland, USA.
Johns Hopkins Medicine · USCase Western Reserve University · USJohns Hopkins University · USNational Institute on Aging · USUniversity of Chicago · US

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Investigating Effect of Air pollution and Host Defenses in SARS-CoV2 infectionU01ES026721 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM, RAJAGOPALAN, SANJAY · 2016 to 2020
$3.8M
The Role of Nrf2 in Stabilizing the Epithelial Barrier in Particulate Matter Induced RhinosinusitisR01AI143731 · NIAID · JOHNS HOPKINS UNIVERSITY · PI RAMANATHAN, MURUGAPPAN · 2019 to 2023
$2.2M
VCU NIGMS Mentoring supplementT32GM144294 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI David Delmar Limbrick · 2022 to 2026
$1.3M
NIAID NIH HHS R01 AI143731NIEHS NIH HHS P30 ES027792NIEHS NIH HHS U01 ES026721NIGMS NIH HHS T32 GM144294
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Air PollutantsAir PollutionNF-E2-Related Factor 2AnimalsDisease Models, AnimalEnvironmental ExposureEpigenesis, GeneticEpitheliumMiceParticulate MatterAir PollutantsNF-E2-Related Factor 2Particulate Matterair pollutionbiomarkerchronic rhinosinusitis

Identifiers

PMID35426488
PMCPMC9790744
OpenAlexW4223946593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.