Evidence map›Paper›PMID 35426467›Full record

ArticleMagnetic resonance in medicine2022

Hyperpolarized

Kasper Hansen, Esben Søvsø S Hansen, Nichlas Riise V Jespersen, Hans Erik Bøtker, Michael Pedersen, Tobias Wang, Christoffer Laustsen

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Stable electron-irradiated [1-Science advances · 2025
    Article
  2. HyperpolarizedMagnetic resonance in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kasper HansenComparative Medicine Lab, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-8669-8897
Esben Søvsø S HansenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Nichlas Riise V JespersenCardiology, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Hans Erik BøtkerCardiology, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Michael PedersenComparative Medicine Lab, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Tobias WangZoophysiology, Department of Biology, Aarhus University, Aarhus, Denmark.
Christoffer LaustsenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-8427-169X
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHyperpolarized

methodsIn the present study, we use this technique to characterize the metabolic fate of hyperpolarized [1-

resultsWe demonstrate a fivefold elevation of the whole-body lactate-to-pyruvate ratio in digesting snakes, pointing to a large rise in lactate production from pyruvate. Consistent with the well-known metabolic stimulation of digestion, measurements of mitochondrial respiration in hepatocytes in vitro indicate a marked postprandial upregulation of mitochondrial respiration. We observed that a low SNR of the hyperpolarized

conclusionWe confirm the large postprandial rise in the wet mass of most visceral organs, except for the heart, and demonstrated that it is possible to image the [1-

Indexed as

BoidaePyruvic AcidAnimalsCarbon IsotopesDigestionLactic AcidMagnetic Resonance ImagingMammalsSwineCarbon IsotopesLactic AcidPyruvic Acid[1-13C]pyruvatemetabolismMRIpostprandialpythonreptile

Identifiers

PMID35426467
PMCPMC9321735
OpenAlexW4224017475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.