Observational studyJournal of thrombosis and haemostasis : JTH2022
Venous thrombosis risk during and after medical and surgical hospitalizations: The medical inpatient thrombosis and hemostasis (MITH) study.
Observational study in Journal of thrombosis and haemostasis : JTH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Global burden of venous thromboembolism: incidence and outcome estimates of deep-vein thrombosis and pulmonary embolism.Nature reviews. Cardiology · 2026Review
- External validation of the Intermountain Risk Scores for postdischarge thrombosis and bleeding in an independent population.Research and practice in thrombosis and haemostasis · 2026Article
- Deep Vein Thrombosis Prevention in Acute Ischemic Stroke Patients with Lower Limb Paralysis: A Narrative Review.Journal of clinical medicine · 2026Review
- Current Trends in Venous Thromboprophylaxis for Inpatient Care.Journal of personalized medicine · 2026Review
- Implementation of the Maynard-Based Risk Assessment Model for Venous Thromboembolism Inpatient Prophylaxis: A Before-and-After Study.Healthcare (Basel, Switzerland) · 2025Article
- Evaluation of factors underlying differences in venous thromboembolism rates between Black and White patients.Journal of vascular surgery. Venous and lymphatic disorders · 2025Article
- Incidence of and risk factors for hospital-acquired bleeding in people with cancer: a systematic review.Research and practice in thrombosis and haemostasis · 2025Article
- Anticoagulation and other risk factors for clinically relevant bleeding after medical hospitalization: the Medical Inpatient Thrombosis and Hemostasis Study.Journal of thrombosis and haemostasis : JTH · 2025Article
- Risk factors for venous thrombosis after discharge from medical hospitalizations: the Medical Inpatient Thrombosis and Hemostasis study.Journal of thrombosis and haemostasis : JTH · 2025Article
- Impact of a Clinical Decision Support System on CT Pulmonary Angiography Yield and Utilization in Hospitalized Patients.Journal of the American College of Radiology : JACR · 2025Article
- Same-day emergency care: a retrospective observational study of the incidence and predictors of venous thromboembolism following hospital-based acute ambulatory medical care.Journal of thrombosis and haemostasis : JTH · 2025Observational
- Assessing Venous Thromboembolism Incidence and Risk Factors: a Narrative Review.Materia socio-medica · 2025Article
- Application of machine learning to predict the occurrence of venous thromboembolism in patients hospitalized for coronary artery disease: a single-center retrospective study.Frontiers in cardiovascular medicine · 2025Article
- Validation of the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) risk scores for venous thromboembolism and bleeding in an independent population.Research and practice in thrombosis and haemostasis · 2024Article
- Development and validation of a risk model for hospital-acquired venous thrombosis: the Medical Inpatients Thrombosis and Hemostasis study.Journal of thrombosis and haemostasis : JTH · 2024Article
- Effectiveness and cost effectiveness of pharmacological thromboprophylaxis for medical inpatients: decision analysis modelling study.BMJ medicine · 2024Article
- Effectiveness, Safety, and Costs of Thromboprophylaxis with Enoxaparin or Unfractionated Heparin Among Medical Inpatients With Chronic Obstructive Pulmonary Disease or Heart Failure.Journal of health economics and outcomes research · 2024Article
- Occurrence of Hospital-Associated Thrombosis in the Setting of Current Thromboprophylaxis Strategies: An Observational Cross-Sectional Study.TH open : companion journal to thrombosis and haemostasis · 2023Article
- Epidemiology and prevention of venous thromboembolism.Nature reviews. Cardiology · 2023Review
- The relative risk of bleeding after medical hospitalization: the medical inpatient thrombosis and hemorrhage study.Journal of thrombosis and haemostasis : JTH · 2023Observational
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundThirty to seventy percent of all venous thromboembolism (VTE) events are associated with hospitalization. The absolute and relative risks during and after hospitalization are poorly characterized.
objectivesQuantify the absolute rate and relative risk of VTE during and up to 3 months after medical and surgical hospitalizations. PATIENTS/
methodsWe conducted an observational cohort study between 2010 and 2016 of patients cared for by the University of Vermont (UVM) Health Network's primary care population. Cox proportional hazard models with hospitalization modeled as a time-varying covariate were used to estimate VTE risk.
resultsOver 4.3 years of follow-up, 55 220 hospitalizations (156 per 1000 person-years) and 713 first venous thromboembolism events (2.0 per 1000 person-years) occurred. Among individuals not recently hospitalized, the rate of venous thromboembolism was 1.4 per 1000 person-years and 71.8 per 1000 person-years during hospitalization. During the first, second, and third months after discharge, the rates of venous thromboembolism were 35.1, 11.3, and 5.2 per 1000 person-years, respectively. Relative to those not recently hospitalized, the age- and sex-adjusted HRs of venous thromboembolism were 38.0 (95% CI 28.0, 51.5) during hospitalization, and 18.4 (95% CI 15.0, 22.6), 6.3 (95% CI 4.3, 9.0), and 3.0 (95% CI 1.7, 5.4) during the first, second, and third months after discharge, respectively. Stratified by medical versus surgical services the rates were similar.
conclusionHospitalization and up to 3 months after discharge were strongly associated with increased venous thromboembolism risk. These data quantify this risk for use in future studies.
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