Evidence map›Paper›PMID 35426014›Full record

ArticleIrish journal of medical science2023

Renal tubular dysfunction in COVID-19 patients.

Gustavo Aroca-Martínez, Lil Avendaño-Echavez, Carlos Garcia, Daniela Ripoll, Daniela Dianda, Andrés Cadena-Bonfanti, Carlos G Musso

Open access · bronzeAbstract read
In one paragraph

Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gustavo Aroca-MartínezFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
Lil Avendaño-EchavezFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
Carlos GarciaFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
Daniela RipollFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
Daniela DiandaNephrology Department, Clínica de La Costa, Barranquilla, Colombia.
Andrés Cadena-BonfantiFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
Carlos G MussoFacultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia. carlos.musso@hospitalitaliano.org.ar.
Universidad Simón Bolívar · COUniversity of the Coast · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSARS-CoV-2 infection can affect other organs aside from those of respiratory system, particularly the kidney, heart, blood, digestive tract, and nervous system. COVID-19 renal compromise consists of different syndromes since proteinuria, hematuria, and acute kidney injury (AKI), until chronic kidney disease. Since COVID-19-induced renal tubular damage has been described as a potential antecedent condition to AKI installation, it was decided to evaluate how COVID-19 affects tubular function. MATERIALS AND

methodSerum inflammatory parameters, urinalysis, and classical urinary indexes in COVID-19 admitted patients who had neither AKI nor chronic kidney disease (CKD) were evaluated. Statistical analysis was performed by applying Student t test.

resultsRenal tubular function was evaluated in 41 COVID-19 admitted patients who had neither AKI nor CKD. Patients' mean age was 56 years, males (79%), and with normal creatininemia (0.8 ± 0.2 mg/dL) and eGFR (105.7 ± 6.5 mL/min) values. It was found mild hypocalcemia and a relative increased fractional excretion (FE) of sodium, FE of calcium, FE of phosphorus, calcium-creatinine index, urinary osmolarity, and relative alkaline urine pH values.

conclusionTubular dysfunction was documented in COVID-19 patients.

Indexed as

Acute Kidney InjuryCOVID-19Renal Insufficiency, ChronicCalciumHumansMaleMiddle AgedSARS-CoV-2CalciumCOVID-19ElectrolytesTubular function

Identifiers

PMID35426014
PMCPMC9010058
OpenAlexW4223998218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.