Evidence map›Paper›PMID 35425997›Full record

ArticleMolecular medicine reports2022

NADH dehydrogenase subunit 1/4/5 promotes survival of acute myeloid leukemia by mediating specific oxidative phosphorylation.

Ye Kuang, Chuanmei Peng, Yulin Dong, Jia Wang, Fanbin Kong, Xiaoqing Yang, Yang Wang, Hui Gao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ye KuangDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Chuanmei PengDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Yulin DongDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Jia WangDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Fanbin KongDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Xiaoqing YangDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Yang WangDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Hui GaoDepartment of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China.
Kunming Medical University · CNYan'an Hospital Affiliated To Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a type of hematological malignancy caused by uncontrolled clonal proliferation of hematopoietic stem cells. The special energy metabolism mode of AML relying on oxidative phosphorylation is different from the traditional 'Warburg effect'. However, its mechanism is not clear. In the present study, it was demonstrated that the mRNA expression levels of NADH dehydrogenase subunit 1, 4 and 5 (ND1, ND4 and ND5) were upregulated in AML samples from The Cancer Genome Atlas database using the

Indexed as

Leukemia, Myeloid, AcuteOxidative PhosphorylationAnimalsMiceMice, NudeNADH DehydrogenaseUp-RegulationNADH Dehydrogenaseacute myeloid leukemiaNADH dehydrogenase subunit 1/4/5oxidative phosphorylationproliferation

Identifiers

PMID35425997
PMCPMC9052001
OpenAlexW4224031142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.