Evidence map›Paper›PMID 35425866›Full record

ArticleHealth science reports2022

Association of chronic inflammation with cardiovascular risk in chronic obstructive pulmonary disease-A cross-sectional study.

Đivo Ljubičić, Vedran Balta, Dario Dilber, Hrvoje Vražić, Domagoj Đikić, Dyana Odeh, Jasna Čerkez Habek, Emilija Lozo Vukovac, Neven Tudorić

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Methods to assess atherosclerotic cardiovascular risk in chronic respiratory diseases: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Đivo LjubičićDepartment of Pulmonology Dubrava University Hospital Zagreb Croatia.ORCID 0000-0001-7071-9078
Vedran BaltaFaculty of Science University of Zagreb Zagreb Croatia.ORCID 0000-0002-0424-1173
Dario DilberMagdalena Clinic for Cardiovascular Diseases Krapinske Toplice Croatia.ORCID 0000-0002-0062-4708
Hrvoje VražićUniversity North, University Centre Varaždin Varaždin Croatia.ORCID 0000-0001-8151-9899
Domagoj ĐikićFaculty of Science University of Zagreb Zagreb Croatia.ORCID 0000-0003-0909-3488
Dyana OdehFaculty of Science University of Zagreb Zagreb Croatia.ORCID 0000-0002-6182-755X
Jasna Čerkez HabekClinical Hospital Sveti Duh Zagreb Croatia.ORCID 0000-0003-3177-3797
Emilija Lozo VukovacDepartment of Pulmonology University Hospital Split Croatia.ORCID 0000-0001-6271-4103
Neven TudorićDepartment of Pulmonology Dubrava University Hospital Zagreb Croatia.
University of Zagreb · HRKlinička bolnica "Sveti Duh" · HRUniversity North · HRUniversity of Magdalena · COUniversity of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: COPD is progressive lung disease with known higher cardiovascular (CV) risk, mainly attributed to smoking of cigarettes as the main etiological factor of disease. The aim of this study was to compare CV risk in patients with COPD to control groups of smokers and non-COPD and to investigate the relation of lung function variables, COPD severity, and smoking with Systemic Coronary Risk Estimation (SCORE) risk calculation, arterial stiffness (AS) values, and biological systemic inflammatory markers. Methods: A total of 208 subjects were included in this study: 61 subjects diagnosed with COPD, 83 smokers without COPD, and 64 nonsmokers without COPD. Medical history and clinical data were recorded, including assessment of pulmonary function and AS, calculation of ankle-brachial index, blood analysis, and CV risk assessment by SCORE risk calculation. Results: Subjects with COPD had significantly higher values of SCORE calculation of risk, central aortic pressure, AS, and markers of systemic inflammation compared to control groups of smokers and nonsmokers without COPD ( Conclusion: The results of the research support further identification and research of biological markers and simple specific tests such as arteriography that will enable progress in personalized treatment of patients with COPD and better primary and secondary prevention of comorbidities with the aim of improved treatment outcome.

Indexed as

arterial stiffnessbiological systems inflammatory markerscardiovascular riskCOPDlung function

Identifiers

PMID35425866
PMCPMC8989273
OpenAlexW4223943177

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.