Evidence map›Paper›PMID 35425817›Full record

ArticleFrontiers in cardiovascular medicine2022

Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety.

Jana Haskova, Petr Peichl, Marek Šramko, Jakub Cvek, Lukáš Knybel, Otakar Jiravský, Radek Neuwirth, Josef Kautzner

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  6. Article
  7. Radiation therapy for ventricular arrhythmias.Journal of medical imaging and radiation oncology · 2024
    Review
  8. Article
  9. Repeated stereotactic radiotherapy of recurrent ventricular tachycardia.Clinical and translational radiation oncology · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jana HaskovaDepartment of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czechia.
Petr PeichlDepartment of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czechia.
Marek ŠramkoDepartment of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czechia.
Jakub CvekDepartment of Oncology, University Hospital Ostrava, Ostrava, Czechia.
Lukáš KnybelDepartment of Oncology, University Hospital Ostrava, Ostrava, Czechia.
Otakar JiravskýDepartment of Cardiology, Podlesí Hospital Trinec, Trinec, Czechia.
Radek NeuwirthDepartment of Cardiology, Podlesí Hospital Trinec, Trinec, Czechia.
Josef KautznerDepartment of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czechia.
Institute of Clinical and Experimental Medicine · CZMasaryk University · CZNemocnice Podlesí · CZUniversity Hospital Ostrava · CZUniversity of Ostrava · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotactic body radiotherapy (SBRT) has been reported as an attractive option for cases of failed catheter ablation of ventricular tachycardia (VT) in structural heart disease. However, even this strategy can fail for various reasons. For the first time, this case series describes three re-do cases of SBRT which were indicated for three different reasons. The purpose in the first case was the inaccuracy of the determination of the treatment volume by indirect comparison of the electroanatomical map and CT scan. A newly developed strategy of co-registration of both images allowed precise targeting of the substrate. In this case, the second treatment volume overlapped by 60% with the first one. The second reason for the re-do of SBRT was an unusual character of the substrate-large cardiac fibroma associated with different morphologies of VT from two locations around the tumor. The planned treatment volumes did not overlap. The third reason for repeated SBRT was the large intramural substrate in the setting of advanced heart failure. The first treatment volume targeted arrhythmias originating in the basal inferoseptal region, while the second SBRT was focused on adjacent basal septum without significant overlapping. Our observations suggested that SBRT for VT could be safely repeated in case of later arrhythmia recurrences (i.e., after at least 6 weeks). No acute toxicity was observed and in two cases, no side effects were observed during 32 and 22 months, respectively. To avoid re-do SBRT due to inaccurate targeting, the precise and reproducible strategy of substrate identification and co-registration with CT image should be used.

Indexed as

electroanatomical mappingfailed catheter ablationsafetystereotactic body radiotherapyventricular tachycardia

Identifiers

PMID35425817
PMCPMC9004321
OpenAlexW4220659700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.