Evidence map›Paper›PMID 35425668›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2022

Folk Classification and Factor Rotations: Whales, Sharks, and the Problems With the Hierarchical Taxonomy of Psychopathology (HiTOP).

Gerald J Haeffel, Bertus F Jeronimus, Bonnie N Kaiser, Lesley Jo Weaver, Peter D Soyster, Aaron J Fisher, Ivan Vargas, Jason T Goodson, Wei Lu

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Schizophrenia.Nature reviews. Disease primers · 2025
    Review
  4. Article
  5. "General Addiction Liability" Revisited.Clinical psychological science : a journal of the Association for Psychological Science · 2025
    Article
  6. Article
  7. Article
  8. Philosophy of psychiatry: theoretical advances and clinical implications.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. The nature of psychopathology.JCPP advances · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Hierarchical Taxonomy of Psychopathology (HiTOP) Is Not an Improvement Over the DSM.Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
  19. Answering questions about the Hierarchical Taxonomy of Psychopathology (HiTOP): Analogies to whales and sharks miss the boat.Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gerald J HaeffelUniversity of Notre Dame.
Bertus F JeronimusUniversity of Groningen.
Bonnie N KaiserUniversity of California-San Diego.
Lesley Jo WeaverUniversity of Oregon.
Peter D SoysterUniversity of California-Berkeley.
Aaron J FisherUniversity of California-Berkeley.
Ivan VargasUniversity of Arkansas.
Jason T GoodsonVA Salt Lake City Healthcare Systems.
Wei LuUniversity of Iowa Hospitals and Clinics.

Funding

Circadian and Ultradian Cortisol Rhythms in Chronic Sleep Continuity DisturbanceK23HL141581 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI VARGAS, IVAN · 2019 to 2023
$677k
NHLBI NIH HHS K23 HL141581
6 · The paper itself

Abstract

The Hierarchical Taxonomy of Psychopathology (HiTOP) uses factor analysis to group people with similar self-reported symptoms (i.e., like-goes-with-like). It is hailed as a significant improvement over other diagnostic taxonomies. However, the purported advantages and fundamental assumptions of HiTOP have received little, if any scientific scrutiny. We critically evaluated five fundamental claims about HiTOP. We conclude that HiTOP does not demonstrate a high degree of verisimilitude and has the potential to hinder progress on understanding the etiology of psychopathology. It does not lend itself to theory-building or taxonomic evolution, and it cannot account for multifinality, equifinality, or developmental and etiological processes. In its current form, HiTOP is not ready to use in clinical settings and may result in algorithmic bias against underrepresented groups. We recommend a bifurcation strategy moving forward in which the DSM is used in clinical settings while researchers focus on developing a falsifiable theory-based classification system.

Indexed as

classificationDSMHiTOPhomologymental healthtaxonomytheory

Identifiers

PMID35425668
PMCPMC9004619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.