Evidence map›Paper›PMID 35425568›Full record

ArticleRSC advances2022

Reduced graphene oxide-incorporated calcium phosphate cements with pulsed electromagnetic fields for bone regeneration.

Hoon Seonwoo, Han-Wool Choung, Sangbae Park, Kyoung Soon Choi, Kyoung-Je Jang, Jangho Kim, Ki-Taek Lim, Yeonju Kim, Pankaj Garg, Shambhavi Pandey and 6 more

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. [Research progress of electroactivity graphene-based materials in bone repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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  9. Engineering Functional Graphenic Materials for Bone Repair.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hoon SeonwooDepartment of Covergent Biosystems Engineering, College of Life Science and Natural Resources, Sunchon National University Suncheon 57922 Republic of Korea.
Han-Wool ChoungDepartment of Oral Histology-Developmental Biology, Dental Research Institute and School of Dentistry, Seoul National University Seoul 03080 Republic of Korea woolmania@naver.com jcapark@snu.ac.kr.
Sangbae ParkDepartment of Biosystems & Biomaterials Science and Engineering, Seoul National University Seoul 08826 Republic of Korea sb92park@snu.ac.kr.
Kyoung Soon ChoiAdvanced Nano-Surface Research Group, Korea Basic Science Institute Daejeon 34133 Republic of Korea hanlalai@naver.com.
Kyoung-Je JangDivision of Agro-System Engineering, College of Agriculture and Life Science, Gyeongsang National University Jinju 52828 Republic of Korea kj_jang@gnu.ac.kr.
Jangho KimDepartment of Rural and Biosystems Engineering, Chonnam National University Gwangju 500-757 Republic of Korea rain2000@jnu.ac.kr.ORCID https://orcid.org/0000-0001-9424-8215
Ki-Taek LimDepartment of Biosystems Engineering, Kangwon National University Chuncheon 24341 Republic of Korea ktlim@kangwon.ac.kr.ORCID https://orcid.org/0000-0003-2091-788X
Yeonju KimDepartment of Otolaryngology, Ajou University School of Medicine Suwon 16499 Republic of Korea yeonju0130@naver.com yhc@ajou.ac.kr.
Pankaj GargResearch Institute of Agriculture and Life Sciences, Seoul National University Seoul 08826 Republic of Korea pnkjchem@gmail.com shambhavi16@gmail.com.
Shambhavi PandeyResearch Institute of Agriculture and Life Sciences, Seoul National University Seoul 08826 Republic of Korea pnkjchem@gmail.com shambhavi16@gmail.com.
Juo LeeInterdisciplinary Program in IT-Bio Convergence System, Sunchon National University Suncheon 57922 Republic of Korea uhun906@gmail.com.
Joo-Cheol ParkDepartment of Oral Histology-Developmental Biology, Dental Research Institute and School of Dentistry, Seoul National University Seoul 03080 Republic of Korea woolmania@naver.com jcapark@snu.ac.kr.ORCID https://orcid.org/0000-0002-3162-7557
Yun-Hoon ChoungDepartment of Otolaryngology, Ajou University School of Medicine Suwon 16499 Republic of Korea yeonju0130@naver.com yhc@ajou.ac.kr.
Pill-Hoon ChoungDepartment of Oral and Maxillofacial Surgery and Dental Research Institute, School of Dentistry, Seoul National University Seoul 03080 Republic of Korea facial1004@gmail.com.
Soo Young KimSchool of Chemical Engineering and Materials Science, Chung-Ang University Seoul 06974 Republic of Korea sooyoungkim@cau.ac.kr.ORCID https://orcid.org/0000-0002-0685-7991
Jong Hoon ChungResearch Institute of Agriculture and Life Sciences, Seoul National University Seoul 08826 Republic of Korea pnkjchem@gmail.com shambhavi16@gmail.com.ORCID https://orcid.org/0000-0003-0711-5655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural calcium phosphate cements (CPCs) derived from sintered animal bone have been investigated to treat bone defects, but their low mechanical strength remains a critical limitation. Graphene improves the mechanical properties of scaffolds and promotes higher osteoinduction. To this end, reduced graphene oxide-incorporated natural calcium phosphate cements (RGO-CPCs) are fabricated for reinforcement of CPCs' characteristics. Pulsed electromagnetic fields (PEMFs) were additionally applied to RGO-CPCs to promote osteogenic differentiation ability. The fabricated RGO-CPCs show distinct surface properties and chemical properties according to the RGO concentration. The RGO-CPCs' mechanical properties are significantly increased compared to CPCs owing to chemical bonding between RGO and CPCs. In

Identifiers

PMID35425568
PMCPMC8981265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.