Evidence map›Paper›PMID 35425396›Full record

ArticleRSC advances2022

Tailoring biocompatibility of composite scaffolds of collagen/guar gum with metal-organic frameworks.

Martín Caldera-Villalobos, Denis A Cabrera-Munguía, Juan J Becerra-Rodríguez, Jesús A Claudio-Rizo

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Martín Caldera-VillalobosFacultad de Ciencias Químicas, Universidad Autónoma de Coahuila Ing. Cárdenas Valdez S/N Saltillo Coahuila México mcalderafcq@uadec.edu.mx jclaudio@uadec.edu.mx.ORCID https://orcid.org/0000-0002-6769-4532
Denis A Cabrera-MunguíaFacultad de Ciencias Químicas, Universidad Autónoma de Coahuila Ing. Cárdenas Valdez S/N Saltillo Coahuila México mcalderafcq@uadec.edu.mx jclaudio@uadec.edu.mx.
Juan J Becerra-RodríguezUniversidad Politécnica de Pénjamo Carretera Irapuato - La Piedad Km 44 Pénjamo 36921 Guanajuato México.
Jesús A Claudio-RizoFacultad de Ciencias Químicas, Universidad Autónoma de Coahuila Ing. Cárdenas Valdez S/N Saltillo Coahuila México mcalderafcq@uadec.edu.mx jclaudio@uadec.edu.mx.
Universidad Autónoma de Coahuila · MXPolytechnic University of Puerto Rico · PR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) are microporous materials with high potential for biomedical applications. They are useful as drug delivery systems, antibacterials, and biosensors. Recently, composite materials comprised of polymer matrixes and MOFs have gained relevance in the biomedical field due to their high potential as materials to accelerate wound healing. In this work, we studied the potential applications of composite hydrogels containing MgMOF74, CaMOF74, and Zn(Atz)(Py). The composite hydrogels are biodegradable, being completely degraded after 15 days by the action of collagenase and papain. The composites showed high biocompatibility reaching cell viabilities up to 165.3 ± 8.6% and 112.3 ± 12.8% for porcine fibroblasts and human monocytes, respectively. The composites did not show hemolytic character and they showed antibacterial activity against

Identifiers

PMID35425396
PMCPMC8979324
OpenAlexW4210302319

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.