ArticleRSC advances2022
Tannic acid induces dentin biomineralization by crosslinking and surface modification.
Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 36 citations in OpenAlex.
- The contribution of different types of polyphenols to bonding performance by enhancing the stabilization of the hybrid layer.Clinical oral investigations · 2026Article
- Long-term stabilization of universal adhesive interfaces in blood-contaminated dentin by myricetin and resveratrol: MMP inhibition, remineralization, and chemical compatibility with 10-MDP after 12 months.Clinical oral investigations · 2025Article
- Tannic Acid-Enhanced Gelatin-Based Composite Hydrogel as a Candidate for Canine Periodontal Regeneration.Gels (Basel, Switzerland) · 2025Article
- Biomineralization of dental tissues with natural drugs: a comprehensive review.The Saudi dental journal · 2025Review
- Unleashing the Potential of Tannic Acid in Dentistry: A Scoping Review of Applications.Bioengineering (Basel, Switzerland) · 2025Review
- Tyrosinase-Catalyzed Soy Protein and Tannic Acid Interaction: Effects on Structural and Rheological Properties of Complexes.Gels (Basel, Switzerland) · 2025Article
- The Impact of Tannic Acid Consumption on Bone Mineralization.Metabolites · 2023Review
- Engineered Biomaterials Trigger Remineralization and Antimicrobial Effects for Dental Caries Restoration.Molecules (Basel, Switzerland) · 2023Review
- Remineralization Potential of Three Restorative Glass Ionomer Cements: An In Vitro Study.Journal of clinical medicine · 2023Article
- Bioactivity of Dental Restorative Materials: FDI Policy Statement.International dental journal · 2023Review
- Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9.Computational and structural biotechnology journal · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is currently known that crosslinking agents can effectively improve the mechanical properties of dentin by crosslinking type I collagen. However, few scholars have focused on the influence of crosslinking agents on the collagen-mineral interface after crosslinking. Analysis of the Fourier transform infrared spectroscopy (FTIR) results showed that hydrogen bonding occurs between the tannic acid (TA) molecule and the collagen. The crosslinking degree of TA to collagen reached a maximum 41.28 ± 1.52. This study used TA crosslinked collagen fibers to successfully induce dentin biomineralization, and the complete remineralization was achieved within 4 days. The crosslinking effect of TA can improve the mechanical properties and anti-enzyme properties of dentin. The elastic modulus (mean and standard deviation) and hardness values of the remineralized dentin pretreated with TA reached 19.1 ± 1.12 GPa and 0.68 ± 0.06 GPa, respectively, which were close to those of healthy dentin measurements, but significantly higher than those of dentin without crosslinking (8.91 ± 1.82 GPa and 0.16 ± 0.01 GPa). The interface energy between the surface of collagen fibers and minerals decreased from 10.59 mJ m
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Registered trials
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