Evidence map›Paper›PMID 35425248›Full record

ArticleRSC advances2022

Synthesis of unprotected glyco-alkynones

Mariana P Darbem, Henrique A Esteves, Robert A Burrow, Antônio A Soares-Paulino, Daniel C Pimenta, Hélio A Stefani

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mariana P DarbemDepartamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo Avenida Prof. Lineu Prestes, 580 - Bl. 13 São Paulo 05508-000 Brazil hstefani@usp.br.
Henrique A EstevesYusuf Hamied Department of Chemistry, University of Cambridge Cambridge CB2 1EW UK.
Robert A BurrowDepartamento de Química, Universidade Federal de Santa Maria Santa Maria 97105-340 Brazil.ORCID https://orcid.org/0000-0003-4909-5007
Antônio A Soares-PaulinoDepartamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo Avenida Prof. Lineu Prestes, 580 - Bl. 13 São Paulo 05508-000 Brazil hstefani@usp.br.
Daniel C PimentaInstituto Butantan São Paulo 05503-900 Brazil.
Hélio A StefaniDepartamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo Avenida Prof. Lineu Prestes, 580 - Bl. 13 São Paulo 05508-000 Brazil hstefani@usp.br.ORCID https://orcid.org/0000-0002-7805-2834
Universidade de São Paulo · BRInstituto Butantan · BRUniversidade Federal de Santa Maria · BRUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein we report a novel Mo-catalyzed carbonylative Sonogashira cross-coupling between 2-iodoglycals and terminal alkynes. The reaction displays major improvements compared to a related Pd-catalyzed procedure previously published by our group, such as utilizing unprotected sugar derivatives as starting materials and tolerance to substrates bearing chelating groups. In this work we also demonstrate the utility of the glyco-alkynone products as platform for further functionalization by synthesizing glyco-flavones

Identifiers

PMID35425248
PMCPMC8979075
OpenAlexW4206492486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.