Evidence map›Paper›PMID 35425191›Full record

ArticleRSC advances2022

Albumin grafted coaxial electrosparyed polycaprolactone-zinc oxide nanoparticle for sustained release and activity enhanced antibacterial drug delivery.

W Pamoda Thavish D Perera, D M Ranga K Dissanayake, Janitha M Unagolla, Rangika T De Silva, Sanjaya D N K Bathige, Lakshitha R Pahalagedara

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

W Pamoda Thavish D PereraAcademy of the Sri Lanka Institute of Nanotechnology Nanotechnology and Science Park, Mahenwatte, Pitipana Homagama 10206 Sri Lanka.ORCID https://orcid.org/0000-0001-8068-4569
D M Ranga K DissanayakeSri Lanka Institute of Nanotechnology Nanotechnology and Science Park, Mahenwatte, Pitipana Homagama 10206 Sri Lanka.ORCID https://orcid.org/0000-0002-0321-5942
Janitha M UnagollaDepartment of Bioengineering, College of Engineering, University of Toledo Toledo OH 43607 USA.
Rangika T De SilvaSri Lanka Institute of Nanotechnology Nanotechnology and Science Park, Mahenwatte, Pitipana Homagama 10206 Sri Lanka.
Sanjaya D N K BathigeSri Lanka Institute of Nanotechnology Nanotechnology and Science Park, Mahenwatte, Pitipana Homagama 10206 Sri Lanka.
Lakshitha R PahalagedaraSri Lanka Institute of Nanotechnology Nanotechnology and Science Park, Mahenwatte, Pitipana Homagama 10206 Sri Lanka.
Sri Lanka Institute of Nanotechnology · LKUniversity of Sri Jayewardenepura · LKUniversity of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most serious issues faced by the healthcare sector is the development of multidrug resistance among various pathogens. It is such that developing new and more capable drugs takes far too long to counter such resistance. In order to overcome these concerns, this study focused on improving upon the coaxial electrospraying process by producing cloxacillin loaded albumin polycaprolactone (PCL) with a ZnO coating for sustained and activity enhanced drug delivery. Albumin-grafted, polycaprolactone-coated, zinc oxide-loaded cloxacillin (APCL-CLOX-ZnO) nanoparticles with a diameter of 85-110 nm were obtained

Identifiers

PMID35425191
PMCPMC8978970
OpenAlexW4205172414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.