Evidence map›Paper›PMID 35425048›Full record

ArticleRSC advances2022

Real-time drug release monitoring from pH-responsive CuS-encapsulated metal-organic frameworks.

Bei Liu, Lirong Sun, Xijian Lu, Yuping Yang, Hongshang Peng, Zhaogang Sun, Juan Xu, Hongqian Chu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Enhancing Anticancer Effects: Targeted Doxorubicin Delivery Using UiO-66-NHJournal of materials science. Materials in medicine · 2025
    Article
  2. Metallic nanomedicine in cancer immunotherapy.Acta pharmaceutica Sinica. B · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bei LiuCollege of Science, Minzu University of China Beijing 100081 China.
Lirong SunCollege of Science, Minzu University of China Beijing 100081 China.
Xijian LuCollege of Science, Minzu University of China Beijing 100081 China.
Yuping YangCollege of Science, Minzu University of China Beijing 100081 China.
Hongshang PengCollege of Science, Minzu University of China Beijing 100081 China.ORCID https://orcid.org/0000-0003-0634-3867
Zhaogang SunTranslational Medicine Center, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute Beijing 101149 China sunzhaogang@bjxkyy.cn chuhongqian@bjxkyy.cn.
Juan XuNational Research Institute for Family Planning Beijing 100005 China xujuan@nrifp.org.cn.
Hongqian ChuTranslational Medicine Center, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute Beijing 101149 China sunzhaogang@bjxkyy.cn chuhongqian@bjxkyy.cn.ORCID https://orcid.org/0000-0001-5455-2837
Minzu University of China · CNCapital Medical University · CNTianjin Municipal Research Institute for Family Planning · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Real-time monitoring of drug release behaviors over extended periods of time is critical in understanding the dynamics of drug progression for personalized chemotherapeutic treatment. In this work, we report a metal-organic framework (MOF)-based nanotheranostic system encapsulated with photothermal agents (CuS) and therapeutic drug (DOX) to achieve the capabilities of real-time drug release monitoring and combined chemo-photothermal therapy. Meanwhile, folic acid-conjugated polyethylene glycol (FA-PEG) antennas were connected to the MOF through coordination interactions, endowing the MOF with an enhanced active targeting effect toward cancer cells. It is anticipated that such a theranostic agent, simultaneously possessing tumor-targeting, real-time drug monitoring and effective treatment, will potentially enhance the performance in cancer therapy.

Identifiers

PMID35425048
PMCPMC8992360
OpenAlexW4223978326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.