ReviewRSC advances2022
A comprehensive review on the sources, essentiality and toxicological profile of nickel.
Review in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The preventive and carcinogenic effect of metals on cancer: a systematic review.BMC public health · 2024Pooled it
- Determination of Trace Elements in Maize Flour Consumed in Turkey by ICP-OES and Assessment of Non-Carcinogenic Health Risk.Biological trace element research · 2026Article
- Analysis of Ni, Cu, and Fe in Loose Cosmetic Products: A Preliminary Dermal Exposure and Health Risk Assessment.Toxics · 2026Article
- AtGLYI3 and AtGLYI6 play the major role in nickel stress tolerance in Arabidopsis thaliana.Plant cell reports · 2026Article
- Comparative study on the protective effects of Silybum marianum L. seeds and leaves against nickel chloride induced anemia, liver and kidney injury: an in vivo and in silico approach.Scientific reports · 2026Article
- Dose-Dependent Effects of Nickel on Skeletal Development: Physiological Necessity and the Threshold of Toxicity.International journal of molecular sciences · 2026Article
- Unravelling Mechanisms of Oxinflammation Induced by Heavy Metals.Metabolites · 2026Review
- The Dual Nature of Metals: Essential Nutrients and Environmental Contaminants.International journal of molecular sciences · 2026Review
- Ion transport for simultaneous nickel electrodeposition and sulfuric acid recovery in single-membrane, dual-chamber electrolyzers.RSC advances · 2026Article
- Crystallographic and computational investigation of a bent-core Schiff base Ni(ii) complex with DNA and protein binding studies.RSC advances · 2026Article
- Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles.Protein science : a publication of the Protein Society · 2026Article
- Electroanalytical overview: recent advances in the sensing of arsenic using screen-printed electrochemical platforms.Environmental science. Nano · 2026Review
- Monitoring and assessment of potentially hazardous particles in high-risk workplaces in the production of Ni-Cd batteries.Scientific reports · 2026Article
- Nutrient uptake of two microalgae from culture medium under nickel treatment.Turkish journal of biology = Turk biyoloji dergisi · 2026Article
- Metal carcinogens and cancer: integrating genetic and epigenetic perspectives.Frontiers in oncology · 2026Review
- Metal-Based Therapeutic Approaches for Overcoming Cancer Drug Resistance: Mechanisms, Drug Delivery Strategies, and Clinical Perspectives.Oncology research · 2026Review
- Health Risk Assessment of Dietary Chemical Exposures: A Comprehensive Review.Foods (Basel, Switzerland) · 2025Review
- Potentially toxic elements in the Bangladeshi diet: An assessment of plant-based foods from a rural market.Toxicology reports · 2025Article
- Gastrointestinal-Ocular Toxicity Following Systematic Ingestion of Nickel-Cadmium Contaminated Water in Wistar Rats Demonstrates Possible Health Complications Characterized by Oxidative Stress, Inflammatory and Histological Changes.Biological trace element research · 2025Article
- Potential risks associated with Fe, Zn, Cu, Ni, and Cr contamination in the muscle ofRSC advances · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review contains up-to-date knowledge and recent advancements on the essentiality, sources, and toxicological profile of nickel and its different compounds. Nickel is a recognized essential element for several important biological processes like the healthy growth of plants, animals, and soil/water microbes; though an excess amount of nickel intoxicates flora and fauna. Nickel is found to affect the photosynthetic function of higher plants; it can severely degrade soil fertility and causes many chronic diseases in humans. Due to the huge growth in the nickel industry and consumption of nickel-containing products, environmental pollution has become inevitable by the element nickel and also varieties of its by-products through all the phases of making, utilization and dumping. We have focused on the importance of agenda 2030 (UN 17 SDGs) during the preparation of the write-up and have highlighted goals 3, 6, 8, 9, 11, 12, 13, 14, and 15 by elaborately discussing associated points. The plausible molecular mechanism of nickel toxicity is presented in simple diagrams. The article elaborates on possible methods for remediation of nickel toxicity and the treatment of nickel dermatitis and nickel cancer. Recent advancements in the understanding of the dual aspects of nickel as beneficial and a carcinogen are the key subject of this article.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.