Evidence map›Paper›PMID 35424684›Full record

ArticleRSC advances2022

Cinnamaldehyde-cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde

Bayan Al Tbakhi, Hamdi Nsairat, Walhan Alshaer, Abdulfattah Al-Kadash, Wissam Helal, Lubna Alrawashdeh, Anthony Day, Khaleel I Assaf, Rola Hassouneh, Fadwa Odeh and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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  6. The role and mechanism of cinnamaldehyde in cancer.Journal of food and drug analysis · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Bayan Al TbakhiDepartment of Chemistry, School of Science, The University of Jordan Amman 11942 Jordan f.odeh@ju.edu.jo +962-979250409.
Hamdi NsairatPharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University Amman 19328 Jordan.ORCID https://orcid.org/0000-0001-5916-5879
Walhan AlshaerCell Therapy Center, The University of Jordan Amman 11942 Jordan.ORCID https://orcid.org/0000-0003-2946-7328
Abdulfattah Al-KadashSchool of Medicine, The University of Jordan Amman 11942 Jordan.ORCID https://orcid.org/0000-0002-7163-2051
Wissam HelalDepartment of Chemistry, School of Science, The University of Jordan Amman 11942 Jordan f.odeh@ju.edu.jo +962-979250409.ORCID https://orcid.org/0000-0001-8631-0031
Lubna AlrawashdehDepartment of Chemistry, Faculty of Science, The Hashemite University P. O. Box 330127 Zarqa 13133 Jordan.
Anthony DaySchool of Science, The University of New South Wales Canberra ACT 2600 Australia.ORCID https://orcid.org/0000-0001-5819-9604
Khaleel I AssafDepartment of Chemistry, Al-Balqa Applied University Al-Salt 19117 Jordan.ORCID https://orcid.org/0000-0003-4331-8492
Rola HassounehDepartment of Chemistry, School of Science, The University of Jordan Amman 11942 Jordan f.odeh@ju.edu.jo +962-979250409.
Fadwa OdehDepartment of Chemistry, School of Science, The University of Jordan Amman 11942 Jordan f.odeh@ju.edu.jo +962-979250409.ORCID https://orcid.org/0000-0002-9341-2359
Abeer Al BawabDepartment of Chemistry, School of Science, The University of Jordan Amman 11942 Jordan f.odeh@ju.edu.jo +962-979250409.
University of Jordan · JOAl-Ahliyya Amman University · JOAl-Balqa Applied University · JOHashemite University · JOUniversity of Canberra · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes (CB[7]-Cinn) and their resulting antitumor activity. CB[7]-Cinn inclusion complexes were prepared by a simple experimental approach and fully characterized for their stoichiometry, formation constant, particle size and morphology. Quantum chemical calculations were performed to elucidate the stable molecular structures of the inclusion complexes and their precursors and to investigate the probable stoichiometry and direction of interaction using three different DFT functionals at the 6-31G(d,p) basis set. The UV-vis spectrophotometric titrations as well as the Job plot, based on

Identifiers

PMID35424684
PMCPMC8982175
OpenAlexW4224095055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.