Evidence map›Paper›PMID 35424581›Full record

ArticleRSC advances2022

Antiurease screening of alkyl chain-linked thiourea derivatives:

Sana Yaqoob, Abdul Hameed, Mahmood Ahmed, Muhammad Imran, Muhammad Abdul Qadir, Mahwish Ramzan, Numan Yousaf, Jamshed Iqbal, Muhammad Muddassar

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sana YaqoobH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi Pakistan abdul_hameed8@hotmail.com.
Abdul HameedH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi Pakistan abdul_hameed8@hotmail.com.ORCID https://orcid.org/0000-0003-0211-6819
Mahmood AhmedDepartment of Chemistry, Division of Science and Technology, University of Education College Road Lahore Pakistan mahmoodresearchscholar@gmail.com.ORCID https://orcid.org/0000-0002-2285-7406
Muhammad ImranKAM-School of Life Sciences, FC College (A Chartered University) Lahore Pakistan.ORCID https://orcid.org/0000-0003-0863-9637
Muhammad Abdul QadirSchool of Chemistry, University of the Punjab Lahore Pakistan.
Mahwish RamzanDepartment of Biosciences, COMSATS University Islamabad Park Road Islamabad Pakistan mmuddassar@comsats.edu.pk.
Numan YousafDepartment of Biosciences, COMSATS University Islamabad Park Road Islamabad Pakistan mmuddassar@comsats.edu.pk.
Jamshed IqbalCenter for Advanced Drug Research, COMSATS Institute of Information Technology Abbottabad 22060 Pakistan.
Muhammad MuddassarDepartment of Biosciences, COMSATS University Islamabad Park Road Islamabad Pakistan mmuddassar@comsats.edu.pk.ORCID https://orcid.org/0000-0001-7860-0522
COMSATS University Islamabad · PKUniversity of Karachi · PKGovernment College University, Lahore · PKUniversity of Education · PKUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urease has become an important therapeutic target because it stimulates the pathogenesis of many human health conditions, such as pyelonephritis, the development of urolithiasis, hepatic encephalopathy, peptic ulcers, gastritis and gastric cancer. A series of alkyl chain-linked thiourea derivatives were synthesized to screen for urease inhibition activity. Structure elucidation of these compounds was done by spectral studies, such as IR,

Identifiers

PMID35424581
PMCPMC8981555
OpenAlexW4214687096

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.