Evidence map›Paper›PMID 35424545›Full record

ArticleRSC advances2022

Flumequine-loaded titanate nanotubes as antibacterial agents for aquaculture farms.

Tarek Baati, Mounir Ben Brahim, Abir Salek, Mouna Selmi, Leila Njim, Polona Umek, Aicha Aouane, Mohamed Hammami, Karim Hosni

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Effects of High Concentrations of Flumequine onAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Tarek BaatiLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.ORCID https://orcid.org/0000-0002-6603-5615
Mounir Ben BrahimLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.
Abir SalekLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.
Mouna SelmiLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.
Leila NjimService d'Anatomie Pathologique, CHU de Monastir, Université de Monastir Tunisia.
Polona UmekJožef Stefan Institute Jamova cesta 39 SI-1000 Ljubljana Slovenia.ORCID https://orcid.org/0000-0003-1825-9523
Aicha AouaneCentre de Microscopie Electronique, IBDML campus Luminy Marseille 13000 France.
Mohamed HammamiLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.ORCID https://orcid.org/0000-0003-1947-7610
Karim HosniLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 666.
Centre d’Immunologie de Marseille-Luminy · FRJožef Stefan Institute · SIUniversity of Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flumequine (FLUM), a quinolone-derived antibiotic is one of the most prescribed drugs in aquaculture farms. However, its intensive use becomes worrisome because of its environmental risks and the emergence of FLUM-resistant bacteria. To overcome these problems we propose in this study the encapsulation and the delivery of FLUM by titanate nanotubes (TiNTs). Optimal FLUM loading was reached by suspending the dehydrated powder nanomaterials (FLUM : TiNTs ratio = 1 : 5) in ethanol. The drug entrapment efficiency was calculated to be 80% approximately with a sustained release in PBS at 37 °C up to 5 days. Then FLUM@TiNTs was evaluated for both its

Identifiers

PMID35424545
PMCPMC8981844
OpenAlexW4213041642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.