ArticleRSC advances2021
Enhancing the biological activity of polyoxometalate-peptide nano-fibrils by spacer design.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Lindqvist-type Polyoxometalates Act as Anti-breast Cancer Drugs via Mitophagy-induced Apoptosis.Current medical science · 2024Article
- Bioorthogonal chemistry of polyoxometalates - challenges and prospects.Chemical science · 2024Review
- Synthesis, Characterization, and Antibacterial Activity of Ni-Substituted Krebs-type Sandwich-Tungstobismuthates Functionalized with Amino Acids.Inorganic chemistry · 2023Article
- Nanostrategies for Therapeutic and Diagnostic Targeting of Gastrin-Releasing Peptide Receptor.International journal of molecular sciences · 2023Review
- Modified Bacteriophage for Tumor Detection and Targeted Therapy.Nanomaterials (Basel, Switzerland) · 2023Review
- Polyoxometalate-peptide hybrid materials: from structure-property relationships to applications.Chemical science · 2022Review
- Promising application of polyoxometalates in the treatment of cancer, infectious diseases and Alzheimer's disease.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022Review
- Mechanism of CK2 Inhibition by a Ruthenium-Based Polyoxometalate.Frontiers in molecular biosciences · 2022Article
- Synthesis and crystal structure of bis-[μ-Acta crystallographica. Section E, Crystallographic communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyoxometalates (POMs) and peptides can be conjugated to yield novel bio-hybrids with potential application as nanodrugs. However, the observed POM-induced folding of the peptide prevents its availability towards biological targets. An Anderson-Evans POM was functionalized with a bombesin analog peptide and engineered by adding a tailored hydrophilic and anionic spacer between the two moieties, to make the targeting sequence more accessible and enable an unprecedented cancer cell recognition capability.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.