Evidence map›Paper›PMID 35424395›Full record

ArticleRSC advances2021

Anisotropic microparticles for differential drug release in nerve block anesthesia.

Shivakumar B S, Vignesh Gopalakrishnan-Prema, Gayathri Raju, Sumi E Mathew, Neeraj Katiyar, Deepthy Menon, Sahadev A Shankarappa

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Shivakumar B SCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Vignesh Gopalakrishnan-PremaCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Gayathri RajuCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Sumi E MathewCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Neeraj KatiyarCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Deepthy MenonCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).
Sahadev A ShankarappaCenter for Nanosciences & Molecular Medicine, Amrita Vishwa Vidyapeetham Kochi 682041 Kerala India sahadevs@icloud.com sahadevs@aims.amrita.edu +91 4842 801234 (extn 8705).ORCID https://orcid.org/0000-0002-7302-6362
University of Kochi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microparticle shape, as a tunable design parameter, holds much promise for controlling drug-release kinetics from polymeric microparticulate systems. In this study we hypothesized that the intensity and duration of a local nerve block can be controlled by administration of bupivacaine-loaded stretch-induced anisotropic poly(lactic-

Identifiers

PMID35424395
PMCPMC8694510
OpenAlexW3124020469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.