Evidence map›Paper›PMID 35424300›Full record

ArticleRSC advances2021

Simplification of gold nanoparticle synthesis with low cytotoxicity using a greener approach: opening up new possibilities.

Mehrdad Khatami, Farideh Mosazade, Mohammadali Raeisi, Masoomeh Ghasemi, Zohreh Fazli, Kolsum Arefkia, Rajender S Varma, Fariba Borhani, Sanaz Khatami

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Mehrdad KhatamiNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.ORCID https://orcid.org/0000-0002-7519-6998
Farideh MosazadeNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.
Mohammadali RaeisiNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.
Masoomeh GhasemiNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.
Zohreh FazliNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.
Kolsum ArefkiaNoncommunicable Diseases Research Center, Bam University of Medical Sciences Bam Iran.
Rajender S VarmaRegional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University Šlechtitelů 27 783 71 Olomouc Czech Republic.
Fariba BorhaniMedical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences Tehran Iran faribaborhani@msn.com.
Sanaz KhatamiDepartment of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University Tehran Iran mehrdad7khatami@gmail.com +98 3433257543 +98 3433257316.
Bam University of Medical Sciences · IRTarbiat Modares University · IRInstitute of Medical Ethics · GBMoravská Vysoká Skola Olomouc · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) have diverse applications in the diagnosis and treatment of ailments. This study describes an extremely simplified synthesis of AuNPs using antioxidant-rich pollen extract as a local natural source. Ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM) were used to characterize the synthesized AuNPs; strong UV-vis absorption at 534 nm confirmed their formation, the XRD pattern showed the presence of a crystalline structure, and TEM images showed them to be spherical nanoparticles with an average size of 9.3 ± 2.9 nm. As synthesized AuNPs remained stable for up to two months under laboratory conditions without any sedimentation or change in the absorption value, presumably due to the protection afforded by the capping agents from pollen. AuNPs revealed low toxicity effects on MCF-7 and HUVECs cell lines (with an IC

Identifiers

PMID35424300
PMCPMC8694009
OpenAlexW3119887027

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.