Evidence map›Paper›PMID 35424280›Full record

ReviewRSC advances2021

Recent advances in nanosized metal organic frameworks for drug delivery and tumor therapy.

Junlei Yang, Hui Wang, Jinyao Liu, Mengkui Ding, Xianjin Xie, Xiaoyu Yang, Yaru Peng, Shuang Zhou, Ruizhuo Ouyang, Yuqing Miao

Abstract readReview
In one paragraph

Review in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Novel UiO-NHACS omega · 2023
    Article
  12. Article
  13. Review
  14. Fabrication of binary g-CRSC advances · 2022
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junlei YangInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Hui WangInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Jinyao LiuInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Mengkui DingInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Xianjin XieInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Xiaoyu YangInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Yaru PengInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.
Shuang ZhouCancer Institute, Tongji University School of Medicine Shanghai 200092 China.
Ruizhuo OuyangInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.ORCID https://orcid.org/0000-0003-0562-7569
Yuqing MiaoInstitute of Bismuth Science, University of Shanghai for Science and Technology Shanghai 200093 China ouyangrz@usst.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal organic-frameworks (MOFs) are novel materials that have attracted increasing attention for applications in a wide range of research, owing to their unique advantages including their small particle size, porous framework structure and high specific surface area. Because of their adjustable size, nanoscale MOFs (nano-MOFs) can be prepared as carriers of biotherapy drugs, thus enabling biotherapeutic applications. Nano-MOFs' metal ion catalytic activity and organic group functional characteristics can be exploited in biological treatments. Furthermore, the applications of nano-MOFs can be broadened by hybridization with other materials to form composites. This review focuses on the preparation and recent advances in nano-MOFs as drug carriers, therapeutic materials and functionalized materials in drug delivery and tumor therapy based on the single/multiple stimulus response of drug release to achieve the targeted therapy, offering a comprehensive reference for drug carrier design. At the end, the current challenges and prospects are discussed to provide significant insight into the design and applications of nano-MOFs in drug delivery and tumor therapy.

Identifiers

PMID35424280
PMCPMC8694185

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.