Evidence map›Paper›PMID 35424161›Full record

ReviewRSC advances2021

Minerals in biology and medicine.

Oliver W L Carter, Yingjian Xu, Peter J Sadler

Abstract readReview
In one paragraph

Review in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Horse gram (Frontiers in plant science · 2026
    Review
  3. Enhancement of the Antioxidant Activity ofMolecules (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oliver W L CarterDepartment of Chemistry, University of Warwick Gibbet Hill Road Coventry CV4 7AL UK P.J.Sadler@Warwick.ac.uk.ORCID https://orcid.org/0000-0001-5342-2168
Yingjian XuGoldenKeys High-Tech Materials Co., Ltd, Building B, Innovation & Entrepreneurship Park Guian New Area Guizhou Province 550025 China goldenkeys9996@thegoldenkeys.com.cn.ORCID https://orcid.org/0000-0002-8371-488X
Peter J SadlerDepartment of Chemistry, University of Warwick Gibbet Hill Road Coventry CV4 7AL UK P.J.Sadler@Warwick.ac.uk.ORCID https://orcid.org/0000-0001-9160-1941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural minerals ('stone drugs') have been used in traditional Chinese medicines for over 2000 years, but there is potential for modern-day use of inorganic minerals to combat viral infections, antimicrobial resistance, and for other areas in need of new therapies and diagnostic aids. Metal and mineral surfaces on scales from milli-to nanometres, either natural or synthetic, are patterned or can be modified with hydrophilic/hydrophobic and ionic/covalent target-recognition sites. They introduce new strategies for medical applications. Such surfaces have novel properties compared to single metal centres. Moreover, 3D mineral particles (including hybrid organo-minerals) can have reactive cavities, and some minerals have dynamic movement of metal ions, anions, and other molecules within their structures. Minerals have a unique ability to interact with viruses, microbes and macro-biomolecules through multipoint ionic and/or non-covalent contacts, with potential for novel applications in therapy and biotechnology. Investigations of mineral deposits in biology, with their often inherent heterogeneity and tendency to become chemically-modified on isolation, are highly challenging, but new methods for their study, including in intact tissues, hold promise for future advances.

Identifiers

PMID35424161
PMCPMC8693805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.