Evidence map›Paper›PMID 35424046›Full record

ArticleRSC advances2021

Design, step-economical diversity-oriented synthesis of an N-heterocyclic library containing a pyrimidine moiety: discovery of novel potential herbicidal agents.

Dong Ma, Yang Yin, Ying-Lu Chen, Yi-Tao Yan, Jun Wu

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong MaDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.
Yang YinDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.
Ying-Lu ChenDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.
Yi-Tao YanDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.ORCID https://orcid.org/0000-0003-3624-0826
Jun WuDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.ORCID https://orcid.org/0000-0002-2841-5190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of highly diverse libraries has become of paramount importance for obtaining novel leads for drug and agrochemical discovery. Herein, the step-economical diversity-oriented synthesis of a library of various pyrimidine-N-heterocycle hybrids was developed, in which a 4,6-dimethoxypyrimidine core was incorporated into nine kinds of N-heterocycles. A total of 34 structurally diverse compounds were synthesized

Identifiers

PMID35424046
PMCPMC8698718

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.