Evidence map›Paper›PMID 35423721›Full record

ArticleRSC advances2020

A dual enhanced anti-bacterial strategy based on high chlorin e6-loaded polyethyleneimine functionalized graphene.

Jiangxia Wang, Yuting Yang, Yuanliang Xu, Lifeng Zhao, Lu Wang, Zhengzhi Yin, Huiming Li, Huan Tan, Kunping Liu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Chlorin Activity Enhancers for Photodynamic Therapy.Molecules (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiangxia WangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.
Yuting YangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.
Yuanliang XuCollege of Food and Biological Engineering, Chengdu University Chengdu 610106 China.
Lifeng ZhaoKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.
Lu WangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.
Zhengzhi YinCollege of Biological, Chemical Sciences and Engineering, Jiaxing University Jiaxing 314001 China.
Huiming LiCollege of Food and Biological Engineering, Chengdu University Chengdu 610106 China.
Huan TanKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.
Kunping LiuKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University Chengdu 610106 China liukunping@cdu.edu.cn.ORCID https://orcid.org/0000-0001-9490-2889
Chengdu University · CNJiaxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infection has always been a long-term problem of human history and has nowadays became a severe threat to human health with the appearance of drug-resistant bacteria due to the abuse of antibiotics. In this study, a high chlorin e6 (Ce6) photosensitizer-loaded polyethyleneimine-functionalized graphene (PEI-G) nanocomposite (PEI-G@Ce6) was prepared. The loading capacity of Ce6 on PEI-G@Ce6 was approximately up to 32.91 wt%, which was higher than that of other nanomaterials. The as-prepared PEI-G@Ce6 not only improves the photostability of free photosensitizer Ce6 molecules but also maintains the ability of singlet oxygen generation. Based on the dual enhancement of the physical antibacterial effects of PEI-G and the photodynamic therapy (PDT) antibacterial effects of loaded photosensitizer Ce6, PEI-G@Ce6 exhibited enhanced antibacterial efficiency towards

Identifiers

PMID35423721
PMCPMC8693315
OpenAlexW3114135049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.