ArticleRSC advances2021
Sulfur quantum dot-based "ON-OFF-ON" fluorescence platform for detection and bioimaging of Cr(vi) and ascorbic acid in complex environmental matrices and biological tissues.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 28 citations in OpenAlex.
- Quantum dot sensors for heavy metal detection: from mechanistic design to field deployment: a review.RSC advances · 2026Review
- Microfluidic paper-based analytical extraction devices (µPAEDs): a cost-effective and portable solution for biomarkers, contaminants and VOC detection.Mikrochimica acta · 2025Review
- Development of a Novel Sulfur Quantum Dots: Synthesis,Applied biochemistry and biotechnology · 2024Article
- Research Update of Emergent Sulfur Quantum Dots in Synthesis and Sensing/Bioimaging Applications.Molecules (Basel, Switzerland) · 2022Review
- Synthesis of Fluorescent Sulfur Quantum Dots for Bioimaging and Biosensing.Frontiers in bioengineering and biotechnology · 2022Review
- Sensitive and selective determination of tetracycline in milk based on sulfur quantum dot probes.RSC advances · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Based on an "assembling-fission" principle, stable sulfur quantum dots (SQDs) were synthesized using sublimed sulfur as a precursor and PEG-400 as a passivator. The fluorescence intensities (FIs) of SQDs were efficiently quenched by Cr(vi) due to formation of SQD/Cr(vi) complexes through the inner-filter effect. When ascorbic acid (AA) was introduced into the SQD/Cr(vi) system, SQD fluorescence was restored due to AA-induced reduction of Cr(vi) to Cr(iii). Consequently, a SQD-based "ON-OFF-ON" platform was constructed for sequential detection of Cr(vi) and AA. Under optimized conditions, the FIs of SQDs were linearly dependent on the concentrations of Cr(vi) and AA, yielding linear ranges of 0.005-1.5 and 0.01-5.5 mM with detection limits of 1.5 and 3 μM, respectively, in waters, serum and tablet samples. After a 24 h incubation, the SQDs displayed strong, quenched and recovered blue fluorescence, respectively, in the SQD, SQD/AAO/Cr(vi) and SQD/Cr(vi) systems in live HeLa cells and zebrafish embryos/larvae. A blue fluorescence was displayed in the yolk of zebrafish embryos, and yolk and head of larvae. This study demonstrates the efficacy of SQD systems for environmental and biological applications in complex matrices, and for direct observation of Cr bioaccumulation in organisms by bioimaging.
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Registered trials
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