Evidence map›Paper›PMID 35423483›Full record

ArticleRSC advances2021

A signal-on fluorescent aptasensor based on gold nanoparticles for kanamycin detection.

Yimeng Sun, Tong Qi, Yan Jin, Lijuan Liang, Jianlong Zhao

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Enhanced light harvesting through efficient energy transfer in a pluronic co-polymer scaffolded blend of donor dyes and plasmonic Au-MoSPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Gold/DNA-CuMolecules (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yimeng SunState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences Shanghai 200050 China llj@mail.sim.ac.cn.
Tong QiState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences Shanghai 200050 China llj@mail.sim.ac.cn.
Yan JinState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences Shanghai 200050 China llj@mail.sim.ac.cn.
Lijuan LiangState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences Shanghai 200050 China llj@mail.sim.ac.cn.ORCID https://orcid.org/0000-0002-1255-2764
Jianlong ZhaoState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences Shanghai 200050 China llj@mail.sim.ac.cn.
Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the development, verification and practical application of an aptasensor for the fluorometric detection of kanamycin. Using the nucleic acid aptamer with FAM fluorescent group as the conjugate, using gold nanoparticles as the fluorescence dynamic quenching source, a fluorescence sensor was fabricated through the signal-on method for the micro-detection of kanamycin. The nucleic acid chimera is connected to the fluorophore, and the gold nanoparticles are used as the fluorescence dynamic quenching source under actual conditions. The detection limit of kanamycin is 0.1 pM, and the detection range is 0.1 pM to 0.1 μM. This biosensor works satisfactorily in complex samples with no impurities, which gives this method an obvious advantage over other analytical methods. In addition, the mechanism of action between gold nanoparticles/FAM-aptamer/kanamycin is discussed and studied in depth here. It provides a more thorough analysis and more application possibilities for fluorescence-aptamer biosensing.

Identifiers

PMID35423483
PMCPMC8695508
OpenAlexW3133961113

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.