Evidence map›Paper›PMID 35423372›Full record

ArticleRSC advances2021

Rapid and sensitive determination of doxorubicin in human whole blood by vertically-ordered mesoporous silica film modified electrochemically pretreated glassy carbon electrodes.

Meifang Wang, Jing Lin, Jiawei Gong, Mingchen Ma, Hongliang Tang, Jiyang Liu, Fei Yan

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Meifang WangDepartment of Chemistry, Zhejiang Sci-Tech University 928 Second Avenue, Xiasha Higher Education Zone Hangzhou 310018 PR China feifei19881203@126.com.
Jing LinThe First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023 China.
Jiawei GongDepartment of Chemistry, Zhejiang Sci-Tech University 928 Second Avenue, Xiasha Higher Education Zone Hangzhou 310018 PR China feifei19881203@126.com.
Mingchen MaGuangxi University of Chinese Medicine Nanning 530020 China.
Hongliang TangAffiliated Fangchenggang Hospital, Guangxi University of Chinese Medicine Fangchenggang 538001 China tanghl2004@gxtcmu.edu.cn.
Jiyang LiuDepartment of Chemistry, Zhejiang Sci-Tech University 928 Second Avenue, Xiasha Higher Education Zone Hangzhou 310018 PR China feifei19881203@126.com.ORCID https://orcid.org/0000-0003-3699-1646
Fei YanDepartment of Chemistry, Zhejiang Sci-Tech University 928 Second Avenue, Xiasha Higher Education Zone Hangzhou 310018 PR China feifei19881203@126.com.ORCID https://orcid.org/0000-0002-2822-698X
Zhejiang Sci-Tech University · CNGuangxi University of Chinese Medicine · CNThe First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine · CNTung Fang Design Institute · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct and accurate detection of doxorubicin (DOX) in unprocessed human whole blood is of vital importance in medical diagnosis and monitoring. In this work, we demonstrate the utilization of electrochemically pretreated glassy carbon electrodes (p-GCE) modified with vertically-ordered mesoporous silica films (VMSF) for rapid and sensitive electrochemical detection of DOX. The electrochemically pretreated process is a simple, cost-effective and environmentally friendly approach for improving interface catalytic properties and introducing oxygen-containing groups into the GCE surface, which could be suitable for stably growing VMSF without any adhesive layer simultaneously retaining the underlying electrode activity. Benefiting from the highly sensitive electrode substrate of p-GCE and electrostatic preconcentration effect of VMSF, the present VMSF/p-GCE sensor was able to determine DOX with an ultrahigh sensitivity (23.94 μA μM

Identifiers

PMID35423372
PMCPMC8695326
OpenAlexW3134609688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.