Evidence map›Paper›PMID 35423177›Full record

ReviewRSC advances2021

Growth factor loading on aliphatic polyester scaffolds.

Hong Shen, Xixue Hu

Abstract readReview
In one paragraph

Review in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Advancements in Functional Polymeric Scaffolds for Scar-Free Skin Regeneration.Polymer science & technology (Washington, D.C.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hong ShenBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences Beijing 100190 China shenhong516@iccas.ac.cn +86-10-62581241.ORCID https://orcid.org/0000-0003-4532-4714
Xixue HuCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology Beijing 100190 China huxx@nanoctr.cn +86-10-82545676.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells, scaffolds and growth factors are three elements of tissue engineering. The success of tissue engineering methods relies on precise and dynamic interactions between cells, scaffolds and growth factors. Aliphatic polyester scaffolds are promising tissue engineering scaffolds that possess good mechanical properties, low immunogenicity, non-toxicity, and adjustable degradation rates. How growth factors can be loaded onto/into aliphatic polyester scaffolds and be constantly released with the required bioactivity to regulate cell growth and promote defect tissue repair and regeneration has become the main concern of tissue engineering researchers. In this review, the existing main methods of loading growth factors on aliphatic polyester scaffolds, the release behavior of loaded growth factors and their positive effects on cell, tissue repair and regeneration are introduced. Advantages and shortcomings of each method also are mentioned. It is still a great challenge to control the release of loaded growth factors at a certain time and at a concentration simulating the biological environment of native tissue.

Identifiers

PMID35423177
PMCPMC8694921

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.