Evidence map›Paper›PMID 35422902›Full record

ReviewAmerican journal of translational research2022

Research on natural products from traditional Chinese medicine in the treatment of myocardial ischemia-reperfusion injury.

Wenyu Bu, Zhaoyang Zhang, Dickson Kofi Wiredu Ocansey, Zhihua Yu, Xiao Yang, Zhitong Liu, Xinyu Wang, Yuhe Ke

Open access · greenAbstract readReview
In one paragraph

Review in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Article
  5. Frontiers in immunology · 2025
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wenyu BuThe First Clinical Medical Institute, Hubei University of Chinese Medicine Wuhan 430060, Hubei, China.
Zhaoyang ZhangTaicang Hospital of Traditional Chinese Medicine Suzhou 215400, Jiangsu, China.
Dickson Kofi Wiredu OcanseyKey Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University Zhenjiang 212013, Jiangsu, China.
Zhihua YuDepartment of Cardiology, Wuhan Hospital of Traditional Chinese and Western Medicine Wuhan 430022, Hubei, China.
Xiao YangThe First Clinical Medical Institute, Hubei University of Chinese Medicine Wuhan 430060, Hubei, China.
Zhitong LiuThe First Clinical Medical Institute, Hubei University of Chinese Medicine Wuhan 430060, Hubei, China.
Xinyu WangThe First Clinical Medical Institute, Hubei University of Chinese Medicine Wuhan 430060, Hubei, China.
Yuhe KeThe First Clinical Medical Institute, Hubei University of Chinese Medicine Wuhan 430060, Hubei, China.
Hubei University of Chinese Medicine · CNJiangsu University · CNSuzhou Traditional Chinese Medicine Hospital · CNWuhan City Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial ischemia-reperfusion injury (MIRI) is a complicated pathologic process that involves multiple factors including oxidative stress (free radical damage), inflammatory response, calcium overloading, and apoptosis in cardiomyocytes. According to Traditional Chinese Medicine (TCM), MIRI belongs to the categories of "chest numbness", "palpitations" and "angina pectoris". Present data indicate that the application of TCM in myocardial ischemia-reperfusion injury is promising and continues to attract research attention. While the efficacy of Chinese herbal medicine has been well-proven, the underlying molecular mechanisms remain elusive. The common proven mechanisms of Chinese herbal medicine in the treatment of MIRI include regulating lipid metabolism, protecting mitochondria, and improving energy metabolism, attenuating calcium (Ca

Indexed as

compound Chinese medicineingredients of traditional Chinese medicineMyocardial ischemia-reperfusion injurytraditional Chinese medicine therapy

Identifiers

PMID35422902
PMCPMC8991172
OpenAlexW4225898107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.