Evidence map›Paper›PMID 35422813›Full record

ArticleFrontiers in immunology2022

Cathelicidin-3 Associated With Serum Extracellular Vesicles Enables Early Diagnosis of a Transmissible Cancer.

Camila Espejo, Richard Wilson, Ruth J Pye, Julian C Ratcliffe, Manuel Ruiz-Aravena, Eduard Willms, Barrett W Wolfe, Rodrigo Hamede, Andrew F Hill, Menna E Jones and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Camila EspejoTasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Richard WilsonCentral Science Laboratory, University of Tasmania, Hobart, TAS, Australia.
Ruth J PyeMenzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Julian C RatcliffeLa Trobe University Bioimaging Platform, La Trobe University, Bundoora, VIC, Australia.
Manuel Ruiz-AravenaSchool of Natural Sciences, University of Tasmania, Hobart, TAS, Australia.
Eduard WillmsDepartment of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia.
Barrett W WolfeInstitute for Marine and Antarctic Studies, University of Tasmania, Hobart, TAS, Australia.
Rodrigo HamedeSchool of Natural Sciences, University of Tasmania, Hobart, TAS, Australia.
Andrew F HillDepartment of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia.
Menna E JonesSchool of Natural Sciences, University of Tasmania, Hobart, TAS, Australia.
Gregory M WoodsMenzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
A Bruce LyonsTasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
University of Tasmania · AULa Trobe University · AUVictoria University · AU

Funding

Evolution of cancer transmissionR01GM126563 · NIGMS · WASHINGTON STATE UNIVERSITY · PI STORFER, ANDREW T · 2017 to 2020
$2.3M
NIGMS NIH HHS R01 GM126563
6 · The paper itself

Abstract

The identification of practical early diagnostic biomarkers is a cornerstone of improved prevention and treatment of cancers. Such a case is devil facial tumor disease (DFTD), a highly lethal transmissible cancer afflicting virtually an entire species, the Tasmanian devil (

Indexed as

Extracellular VesiclesFacial NeoplasmsMarsupialiaAnimalsAntimicrobial Cationic PeptidesCathelicidinsEarly Detection of CancerAntimicrobial Cationic PeptidesCathelicidinsanimal modelscathelicidinsearly cancer detectionexosomesinnate immunityliquid biopsymicrovesiclesproteomics

Identifiers

PMID35422813
PMCPMC9004462
OpenAlexW4226148957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.