Evidence map›Paper›PMID 35422803›Full record

ArticleFrontiers in immunology2022

Adult Memory T Cell Responses to the Respiratory Syncytial Virus Fusion Protein During a Single RSV Season (2018-2019).

Brittani N Blunck, Laura S Angelo, David Henke, Vasanthi Avadhanula, Matthew Cusick, Laura Ferlic-Stark, Lynn Zechiedrich, Brian E Gilbert, Pedro A Piedra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Brittani N BlunckDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Laura S AngeloDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
David HenkeDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Vasanthi AvadhanulaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Matthew CusickDepartment of Pathology, University of Michigan, Ann Arbor, MI, United States.
Laura Ferlic-StarkDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Lynn ZechiedrichDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Brian E GilbertDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Pedro A PiedraDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Baylor College of Medicine · USUniversity of Michigan–Ann Arbor · US

Funding

Harnessing Supercoiling to Regulate DNA ActivityR35GM141793 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ZECHIEDRICH, LYNN · 2021 to 2025
$2.1M
S2: Molecular Mechanisms Underlying Fluoroquinolone Susceptibility and ResistanceR01GM115501 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ZECHIEDRICH, LYNN · 2015 to 2018
$1.7M
NIGMS NIH HHS R01 GM115501NIGMS NIH HHS R35 GM141793
6 · The paper itself

Abstract

Respiratory Syncytial Virus (RSV) is ubiquitous and re-infection with both subtypes (RSV/A and RSV/B) is common. The fusion (F) protein of RSV is antigenically conserved, induces neutralizing antibodies, and is a primary target of vaccine development. Insight into the breadth and durability of RSV-specific adaptive immune response, particularly to the F protein, may shed light on susceptibility to re-infection. We prospectively enrolled healthy adult subjects (

Indexed as

Leukocytes, MononuclearRespiratory Syncytial Virus, HumanAdultAntibodies, ViralHumansMemory T CellsReinfectionSeasonsAntibodies, Viralfusion proteininfectionmemory T cellpeptide librarypolyfunctionalityrespiratory syncytial virus (RSV)viral immunity

Identifiers

PMID35422803
PMCPMC9002099
OpenAlexW4220895654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.