Evidence map›Paper›PMID 35422800›Full record

ArticleFrontiers in immunology2022

B-Cell Epitope Mapping of TprC and TprD Variants of

Barbara Molini, Mark C Fernandez, Charmie Godornes, Anastassia Vorobieva, Sheila A Lukehart, Lorenzo Giacani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Frontiers in immunology · 2026
    Article
  3. Review
  4. Frontiers in immunology · 2026
    Review
  5. Article
  6. B-Cell Epitope Mapping of theDiagnostics (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Development and utilization ofbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Evaluation of a minimal array ofMicrobiology spectrum · 2024
    Article
  12. Comprehensive Overview ofCurrent protein & peptide science · 2024
    Review
  13. Review
  14. AlphaFold2 and its applications in the fields of biology and medicine.Signal transduction and targeted therapy · 2023
    Review
  15. Review
  16. Notes on syphilis vaccine development.Frontiers in immunology · 2022
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Barbara MoliniDepartment of Medicine, University of Washington, Seattle, WA, United States.
Mark C FernandezDepartment of Medicine, University of Washington, Seattle, WA, United States.
Charmie GodornesDepartment of Medicine, University of Washington, Seattle, WA, United States.
Anastassia VorobievaVIB-VUB Center for Structural Biology, VIB, Brussels, Belgium.
Sheila A LukehartDepartment of Medicine, University of Washington, Seattle, WA, United States.
Lorenzo GiacaniDepartment of Medicine, University of Washington, Seattle, WA, United States.
University of Washington · USVrije Universiteit Brussel · BE

Funding

University of Washington (UW) Sexually Transmitted Infections (STI) Cooperative Research Center (CRC) - Syphilis Vaccine to Protect against Local and Disseminated T. pallidum InfectionU19AI144133 · NIAID · UNIVERSITY OF WASHINGTON · PI WALD, ANNA · 2019 to 2023
$10.6M
TREPONEMA PALLIDUM PATHOGENESIS ASSOCIATED MOLECULESR01AI042143 · NIAID · UNIVERSITY OF WASHINGTON · PI LUKEHART, SHEILA A. · 1998 to 2015
$5.4M
NIAID NIH HHS R01 AI042143NIAID NIH HHS U19 AI144133
6 · The paper itself

Abstract

Several recent studies have focused on the identification, functional analysis, and structural characterization of outer membrane proteins (OMPs) of

Indexed as

SyphilisTreponemal InfectionsYawsAnimalsEpitope MappingEpitopes, B-LymphocyteHumansImmune SeraRabbitsRecombinant ProteinsTreponema pallidumVaccine DevelopmentEpitopes, B-LymphocyteImmune SeraRecombinant ProteinsB-cell epitope mappingsyphilisTpr proteinsTreponema pallidumvaccine development

Identifiers

PMID35422800
PMCPMC9001972
OpenAlexW4220793408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.