Evidence map›Paper›PMID 35422635›Full record

ArticleInfection and drug resistance2022

Clinico-Epidemio-Microbiological Exploratory Review Among COVID-19 Patients with Secondary Infection in Central India.

T Karuna, Rahul Garg, Shweta Kumar, Gyanendra Singh, Lakshmi Prasad, Kawal Krishen Pandita, Abhijit Pakhare, Saurabh Saigal, Alkesh Kumar Khurana, Rajnish Joshi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Association of COVID with Mycosis in General.Infectious disorders drug targets · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

T KarunaDepartment of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India.
Rahul GargDepartment of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.ORCID 0000-0002-5162-971X
Shweta KumarDepartment of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
Gyanendra SinghDepartment of Community and Family Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
Lakshmi PrasadDepartment of Hospital Administration, AIIMS, Bhopal, Madhya Pradesh, India.ORCID 0000-0002-6297-202X
Kawal Krishen PanditaDepartment of Hospital Administration, AIIMS, Bhopal, Madhya Pradesh, India.
Abhijit PakhareDepartment of Community and Family Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
Saurabh SaigalDepartment of Critical Care, AIIMS, Bhopal, Madhya Pradesh, India.
Alkesh Kumar KhuranaDepartment of Pulmonary Medicine & TB, AIIMS, Bhopal, Madhya Pradesh, India.
Rajnish JoshiDepartment of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
Kamini WaliaIndian Council of Medical Research, New Delhi, India.
Sagar KhadangaDepartment of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
All India Institute of Medical Sciences Bhopal · INIndian Council of Medical Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Secondary infections (SI) in COVID-19 have been documented from 3.6% to 72% in various studies with mortality ranging from 8.1% to 57.6%. There is a gap in knowledge for clinico-epidemio-microbilogical association among COVID-19 patients with concomitant SI. Patients and Methods: This is a retrospective chart review, in central India. The study was undertaken for hospitalized adult patients during 1st June 2020 to 30th November 2020, with laboratory proven COVID-19 infection and secondary infection. Results: Out of the total 2338 number of patients, only 265 (11.3%) patients were investigated for microbiological identification of SI. Male gender was predominant (76.8%) and the mean age was 53.7 ± 17.8 years. Only 3.5% (82/2338) of patients were having microbiologically confirmed (bacterial or fungal) SI. The overall mortality was 50.9% (54/82) with a differential mortality of 88.8% (48/54) in high-priority areas and 21.4% (6/28) in low-priority areas. Blood was the most commonly investigated sample (56%) followed by urine (20.7%) and respiratory secretion (15.8%). Conclusion: There is an urgent need of better anti-microbial stewardship practices in India (institutional and extra institutional) for curtailment of secondary infection rates particularly among COVID-19 patients.

Indexed as

anti-microbial stewardship practiceCOVID-19mortalitypredictorsecondary infection

Identifiers

PMID35422635
PMCPMC9005231
OpenAlexW4225845615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.